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| 成纤维细胞生长因子10在前列腺增生组织中的表达 | |
| 引用本文： | 邱建新,邹炼,李荣. 成纤维细胞生长因子10在前列腺增生组织中的表达[J]. 细胞与分子免疫学杂志, 2002, 18(6): 595-597 |
| 作者姓名： | 邱建新 邹炼 李荣 |
| 作者单位： | 1. 第四军医大学唐都医院泌尿外科,陕西,西安,710038 2. 第二炮兵总医院泌尿外科,北京,100088 3. 第四军医大学基础部医学遗传与发育生物学教研室,陕西,西安,710038 |
| 摘 要： | 目的 检测前列腺增生组织中成纤维细胞生长因子10（FGF－10）的表达，探讨其在前列腺增生中的作用。方法 应用半定量R－TPCR技术和免疫组织化学方法，检测20例前列腺增生组织中FGF－10的表达，并与正常的前列腺组织进行比较。结果 前列腺增生组织中FGF－10 mRNA的水平高于正常前列腺组织，前列腺增生组织中FGF－10 mRNA的水平高于正常前列腺组织；前列腺组织中均见FGF－10阳性染色，前列腺增生组织中表达显著高于正常的前列腺组织。结论 前列腺增生组织中FGF－10的表达高于正常前列腺组织，提示FGF－10对促进前列腺的增生起重要作用。 |
| 关 键 词： | 成纤维细胞生长因子10 前列腺增生 RT－PCR 免疫组织化学 基因表达 |
| 文章编号： | 1007-8738(2002)06-595-03 |
The significance of fibroblast growth factor 10 mRNA expression in benign prostate hyperplasia tissue |
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| QIU Jian xin ,ZOU Lian ,LI Rong. The significance of fibroblast growth factor 10 mRNA expression in benign prostate hyperplasia tissue[J]. Chinese journal of cellular and molecular immunology, 2002, 18(6): 595-597 | |
| Authors: | QIU Jian xin ZOU Lian LI Rong |
| Affiliation: | QIU Jian xin 1,ZOU Lian 2,LI Rong 3 1 Department of Urology,Tangdu Hospital,3Department of Genetics and Development Biology,Fourth Military Medical University,Xi'an 710038,Shaanxi Province, 2Department of Urology,Second Rocket Army General Hospital,Beijing 100088,China |
| Abstract: | Aim To determine expression of fibroblast growth factor 10 (FGF 10) in benign prostate hyperplasia tissue. Methods The expression levels of FGF 10 mRNA in benign prostate hyperplasia and normal prostate tissues were detected by semi quantitive RT PCR, while the expression level of FGF 10 protein were detected by immunohistochemcal staining and quantitative analysis. Results The expression levels of both FGF 10 mRNA and protein in benign prostate hyperplasiatissue were higher than those in normal prostate tissues. Conclusion FGF 10 may play an important role in benign prostate hyperplasia tissue. |
| Keywords: | fibroblast growth factor benign prostate hyperplasia expression |
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