不同类型心力衰竭血浆B型尿钠肽浓度比较

目的 :比较不同类型心力衰竭时血浆B型尿钠肽 (BNP)浓度。方法 :对 14 9例未正规抗心力衰竭患者测定BNP并根据临床资料和超声心动图将患者分成 3种类型 :左室舒张功能不全 ,左室收缩功能不全和右室收缩功能不全 ,比较 3种类型心力衰竭时的BNP值。结果 :4 8例左室舒张功能不全BNP值 (115± 80 )pg ml,6 2例左室收缩功能不全BNP值 (5 16± 4 4 5 )pg ml,39例右室收缩功能不全BNP值 (345± 184 )pg ml,3组患者间有统计学差异 (P <0 0 5 )。结论 :不同类型心力衰竭BNP值增高程度不同 ,以左室收缩功能不全BNP值增高最为明显 ,右室收缩功能不全次之 ,左室舒张功能不全最低 ,结合其他临床资料 ,BNP浓度有助于心力衰竭类型的判断

The comparison of the B-type natriuretic peptide plasma levels among varied types of heart failure

Objective:To investigate the B-type natriuretic peptide (BNP) plasma levels among varied types of heart failure.Method:149 patients who did not undergo regular anti-heart-failure therapy were included.BNP plasma levels were measured just before echocardiography by a rapid point-of-care assay.The patients were divided into left ventricular diastolic dysfunction,left ventricular systolic dysfunction and right ventricular systolic dysfunction.Result:The mean BNP level in 48 patients with left ventricular diastolic dysfunction is (115±80) pg/ml,in 62 patients with left ventricular systolic dysfunction is (516±445) pg/ml,in 39 patients with right ventricular systolic dysfunction is (345±184) pg/ml.(P<0^05)Conclusion:The BNP plasma levels are different among varied types of heart failure.Left ventricular systolic dysfunction has the highest BNP level and left ventricular diastolic dysfunction has the lowest BNP level.BNP levels contribute to the diagnosis of the type of heart failure when combined with other clinic data.