Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethylamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5-BrU)ACG)2 at 1.3-A resolution |
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Authors: | Todd A K Adams A Thorpe J H Denny W A Wakelin L P Cardin C J |
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Affiliation: | Chemistry Department, University of Reading, Whiteknights, Reading RG6 6AD, U.K. |
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