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| 喉鳞癌中hMLH1和hMSH2蛋白的表达及意义 | |
| 引用本文： | 任颖川,张超,李芦二永,李永萍. 喉鳞癌中hMLH1和hMSH2蛋白的表达及意义[J]. 河南科技大学学报(医学版), 2008, 26(3) |
| 作者姓名： | 任颖川 张超 李芦二永 李永萍 |
| 作者单位： | 河南科技大学第一附属医院,河南洛阳,471003;河南科技大学第一附属医院,河南洛阳,471003;河南科技大学第一附属医院,河南洛阳,471003;河南科技大学第一附属医院,河南洛阳,471003 |
| 摘 要： | 目的 探讨喉鳞癌和声带息肉中hMLH1和hMSH2蛋白的表达及意义.方法 采用免疫组化法检测喉鳞癌和声带息肉中hMLH1和hMSH2蛋白的表达.结果 在喉鳞癌中hMLHl和hMSH2蛋白的阳性率为56.86%、58.82%,显著低于声带息肉81.25%、87.50%,差异具有统计学意义(P |
| 关 键 词： | 喉鳞癌 人类错配修复基因1 人类错配修复基因2 免疫组织化学 |
Expression and Significance of hMLH1 and hMSH2 Protein in Laryngeal Squamous Cell Carcinoma |
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| REN Ying-chuan,ZHANG Chao,LU Er-yong,et al. Expression and Significance of hMLH1 and hMSH2 Protein in Laryngeal Squamous Cell Carcinoma[J]. Journal of Henan University of Science & Technology:Medical Science, 2008, 26(3) | |
| Authors: | REN Ying-chuan ZHANG Chao LU Er-yong et al |
| Affiliation: | REN Ying-chuan,ZHANG Chao,LU Er-yong,et al(First Affiliated Hospital,Henan University of Science , Technology,Luoyang 471003,China) |
| Abstract: | Objective To explore the relationship between the expression of hMLH1,hMSH2 in laryngeal squamous cell carcinoma and vocal cord polyps. Methods The expression of hMLH1 and hMSH2 protein were detected by immunohistochemistry SP method. Results The expression positive rates of hMLH1 and hMSH2 in laryngeal carcinoma was 56.86%,58.82%,was lower than the rates in vocal cord polyps 81.25%,87.50%,there was significant difference between them(P<0.05).The expression of hMLH1 and hMSH2 was related with differentiatio... |
| Keywords: | laryngeal squamous cell carcinoma hMLH1 hMSH2 immunohistochemistry |
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