| 局部应用氨甲喋呤和卡介苗预防膀胱癌术后复发(附18例报告) |
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| 引用本文： | 陈铁峰,王绪保.局部应用氨甲喋呤和卡介苗预防膀胱癌术后复发(附18例报告)[J].临床泌尿外科杂志,2000,15(9):402-403. |
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| 作者姓名： | 陈铁峰 王绪保 |
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| 作者单位： | 1. 天水市第二人民医院泌尿外科,甘肃天水,741020
2. 天水市北道区中医院中西医结合科 |
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| 摘 要： | 目的：探讨局部应用氨甲喋呤（ＭＴＸ），卡介苗（ＢＣＧ）预防膀胱癌术后复发的疗效。方法：对１３例浅表性膀胱癌和５例浸润性膀胱癌施以膀胱部分切除术，术前行ＭＴＸ膀胱灌注，术中和术后分别行ＭＴＸ膀胱粘膜下注射和直肠粘膜下注射，术后行小剂量ＢＣＧ膀胱灌注，结果：全部病蜊到随访，时间为６￣４０个月，平均２８个月。３例复发，复发率１６．７％。结论：该疗法可以增加膀胱癌患者保留膀胱的治疗机会，为膀胱癌的治疗提供
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| 关 键 词： | 膀胱移行细胞癌 切除术 复发 卡介苗 氨甲喋呤 |
| 修稿时间： | 1999-09-22 |
MTX and BCG in treatment and prevention of bladder tumor |
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| CHEN Tie-feng,WANG Xiu-bao.MTX and BCG in treatment and prevention of bladder tumor[J].Journal of Clinical Urology,2000,15(9):402-403. |
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| Authors: | CHEN Tie-feng WANG Xiu-bao |
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| Abstract: | Purpose:To investigate the treatment and prevention of MTX and BCG in bladder cancer. Methods: Partial cystectomy has been carried out for 13 cases of superficial bladder tumor and 5 cases of infiltrative cancer from April 1993 to December 1996.Before and in operation,intravesical instillation and submucosal local infiltrative injection with MTX have been used seperately.After operation rectal submucosal injection of MTX and intravesical minor BCG instillation have been adopted for 18 cases tumor.Results:The mean follow-up has been ranging from 6 to 40 months with 3 recurrence ( 16.7 %) for all cases.Conclusions:The therapy may increase the chance of bladder preservation for infiltrative tumor which may be effective in bladder tumor. |
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| Keywords: | Bladder neoplasms Transitional cell carcinoma Cystectomy Neoplasm recurrence Amethopterin BCG vaccine |
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