| 乳核分散片纯化工艺优化研究 |
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| 引用本文： | 万艳群,欧阳荣,罗懿.乳核分散片纯化工艺优化研究[J].亚太传统医药,2013,9(1):54-57. |
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| 作者姓名： | 万艳群 欧阳荣 罗懿 |
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| 作者单位： | 1. 湖南中医药大学药学院,湖南长沙,410073
2. 湖南中医药大学第一附属医院,湖南长沙,410073 |
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| 基金项目： | 湖南省中医药科研计划项目(201166) |
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| 摘 要： | 目的:优选乳核分散片水提液纯化的最佳工艺条件。方法:以橙皮苷、芍药苷的含量为评价指标,将醇沉法与ZTC1+1澄清剂吸附法进行比较,优选最佳纯化工艺条件。结果:最佳纯化工艺为醇沉,具体方法为:水提液浓缩至相对密度为1.20,含醇量为80%,静置12h。结论:乳核分散片的纯化工艺醇沉法优于ZTC1+1澄清剂吸附法。
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| 关 键 词： | 乳核分散片 醇沉法 澄清剂吸附法 综合评分 |
Optimization on Purification process of Ruhe Dispersible Tablets |
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| Wan Yanqun
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Ouyang Rong
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Luo Yi.Optimization on Purification process of Ruhe Dispersible Tablets[J].Asia-Pacific Traditional Medicine,2013,9(1):54-57. |
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| Authors: | Wan Yanqun Ouyang Rong Luo Yi |
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| Institution: | 1(1.Hunan University of Traditional Chinese Medicine,Changsha 410073,China; 2.The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine,Changsha 410073,China) |
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| Abstract: | Objective：To optimize the purification process of Ruhe dispersible tablets. Methods：With the ingredients of hesperidin , paeoniflorin as the evaluation index, ethanol precipiaton methods were compared with ZTC1 ＋ 1 clarificant agents, to choose the optimize purification process. Results：The optimum process conditions were alcohol precipitation, The specific method was the relative density of the water to be condensed to 1.20,adding ethanol to 70 % of ethanol concentration and depositing 12 hours. Conclusion： Ethanol precipiaton methods were better than ZTC1 ＋ 1 clarificant agents for Ruhe dispersible tablets. |
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| Keywords: | Ruhe Dispersible Tablets Ethanol Precipiaton Clarificant Agents Comprehensive Scoring Method |
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