特利加压素治疗肝硬化难治性腹腔积液的疗效分析

目的 总结并分析特利加压素治疗肝硬化难治性腹腔积液的疗效.方法 回顾性分析2010年8月至2011年4月我院普外科使用特利加压素治疗的25例肝硬化难治性腹腔积液患者的临床资料.结果 本组23例患者治疗后腹腔积液有明显减退,2例患者治疗无效,有效率92.0％；尿量由平均916.7ml/d增至平均2150ml/d.动脉压由平均75.5 mm Hg(1 mm Hg=0.133 kPa)升至平均84 mm Hg;4例患者首次用药后有短暂的腹痛；1例患者发生高血压,暂停用药后恢复.结论 使用特利加压素治疗肝硬化难治性腹腔积液安全有效.

Efficiency analysis of terlipressin in treating cirrhosis patients with refractory ascites

Objective To summarize and analyze the efficiency of terlipressin in treating cirrhosis patients with refractory ascites. Methods The data of 25 cirrhosis patients with refractory ascites treated between Aug 2010 and Apr 2011 were analyzed retrospectively. Results Twenty-three patients had significant decrease in ascites volume. 2 patients had no response to Terlipressin; the efficient rate was 92%. The mean urine excretion increased from mean 2150 ml/d before treatment to mean 916. 7 ml/d after treatment. The arterial pressure increased from mean 75.5 mm Hg to mean 84 mm Hg. 4 patients underwent transient abdominal cramps after the first injection of Terlipressin. There was 1 case of hypertension and the patient recovered when injection ceased. Conclusion Terlipressin is safe and efficient in treating cirrhosis patients with refractory ascites.