精神分裂症的抑郁症状

为了探讨精神分裂症抑郁症状发生率及其相关因素,对159例精神分裂症患者在疗前和疗后8周进行了阳性症状量表(SAPS)、阴性症状量表(SANS)和Hamilton抑郁量表(HAMD)评定,并对抑郁症状的相关因素进行了分析。结果显示,精神分裂症患者的抑郁症状发生率为60.38%;抑郁症状与阳性症状(SAPS总分)、住院次数和自杀未遂发生率有显著相关,而与阴性症状(SANS总分)和疗效无明显相关。作者认为抑郁症状是精神分裂症症状的组成部分,一般不需合并抗抑郁剂治疗。

A Study on Depressive Symptoms of Schizophrenia

Our purpose of this study was to determine the prevalence and its correlative factors of depressive symptoms in schizophrenia. 159 cases with schizophrenia were evaluated with Scale for Assessment of Positive Symptom (SAPS), Scale for Assessment of Negative Symptoms (SANS) and Hamilton Depression Rating Scale (HAMD) before and eight weeks after treatment. The correlative factors of depressive symptoms in schizophrenia were studied by logistic regression. The results showed that the prevalence of depressive symptoms in patients with schizophrenia was 60. 38%. Depressive symptoms correlated with positive symptoms, the frequent of the hospitalization and the prevalence of suicidal behavior. Depressive symptoms not correlated with negative symptoms and the therapeutic effects.The authors were of opinion that the depressive, symptoms might be an integral part of schizophrenia. and anfidepresants might be not necessarily indicated.