普拉洛芬滴眼液治疗干眼症疗效观察

目的：观察1g/L普拉洛芬滴眼液治疗干眼症的疗效。方法：选择我院2011-01/12门诊诊断为干眼症的患者100例,随机分成A、B两组,A组：1g/L普拉洛芬滴眼液及1g/L玻璃酸钠滴眼液联合应用,4次/d点眼,1滴/次。B组：1g/L玻璃酸钠滴眼液单独应用,4次/d点眼,1滴/次。试验疗程为14d。所有的患者符合入选标准,用药前及用药后14d观察患者的问卷评分、SchirmerI试验、角膜荧光素染色评分。比较两组的结果,进行统计分析。结果：1g/L普拉洛芬滴眼液及1g/L玻璃酸钠滴眼液联合应用治疗干眼症患者的效果明显优于单纯使用1g/L玻璃酸钠滴眼液治疗组,两组结果差异有统计学意义。结论：1g/L普拉洛芬滴眼液治疗干眼症,对于缓解症状,改善角膜情况效果良好。

Efficacy of pranoprofen eye drops in dry eyes patients

AIM：To observe the effect of 1g/L pranoprofen eye drops in the treatment of dry eye.METHODS：A total of 100 dry eyes patients,from the outpatient department in our hospital between January and December of 2011,were randomly divided into two groups：group A was treated by 1g/L pranoprofen drops combined with 1g/L sodium hyaluronate eye drops,1 drop each time,4 times/d for each eye;group B was treated by 1g/L sodium hyaluronate eye drops alone,1 drop each time,4 times/d,for each eye,All patients met the inclusion criteria before treatment and were observed before and after 14 days of treatment with questionnaire scores,Schirmer Ⅰ trial,corneal fluorescein staining scores.The results of the two groups were compared for statistical analysis.RESULTS：：The effect of 1g/L pranoprofen eye drops combined 1g/L of sodium hyaluronate eye drops was significantly better than that of 1g/L of sodium hyaluronate eye drops in the treatment of dry eye patients.There was significant difference between two groups.CONCLUSION：1g/L pranoprofen is effective for dry eye to relieve symptoms and improve corneal situation.