Infantile fibrosarcoma: radiological and clinical features |
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Authors: | Dr S J Vinnicombe BSc MRCP FRCR C M Hall FRCR |
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Institution: | (1) Department of Radiology, St. George's Hospital, Blackshaw Road, SW170QT London, UK;(2) Department of Radiology, Hospital for Sick Children, London, UK |
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Abstract: | Two cases of infantile fibrosarcoma are described. This rare childhood malignancy of mesodermal origin usually affects the
lower limbs, as it did in both of our cases. Previously, the only treatment option available involved some form of radical
and often mutilating surgery. More recently, combination chemotherapy has given good results, with the effect that various
imaging modalities have become important in assessing both the initial extent of disease and the response to treatment. Computed
tomography has the advantage of demonstrating the amount of osseous involvement, but at the expense of a considerable dose
of ionizing radiation. On the other hand, magnetic resonance imaging, with its multiplanar capacity, gives superior demonstration
of breaching of tissue planes, which has important implications for planning of surgery. However, as in other soft tissue
tumours, changes in signal characteristics with treatment have proved less specific than was originally anticipated. |
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Keywords: | Infantile Fibrosarcoma Computed tomography Magnetic resonance imaging |
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