108例汶川地震伤感染病例病原学分布及耐药性

目的 了解5.12地震伤感染病例的病原学分布及耐药性情况.方法 收集我院汶川大地震中108例开放性创伤合并感染患者的139份临床标本进行细菌培养和鉴定,并用纸片扩散法对分离阳性的菌株进行药敏检测.结果 共分离96株菌,大多分离自创面分泌物(79.86%),主要来自于骨科(58.33%).分离率较高的依次为不动杆菌(20株)、阴沟肠杆菌(20株)、大肠埃希菌(17株)、葡萄球菌(13株).革兰阴性菌对亚胺培南、阿米卡星、头孢哌酮/舒巴坦耐药率较低.结论 这次地震伤病情复杂.革兰阴性菌对亚胺培南、阿米卡星、头孢哌酮/舒巴坦耐药率较低,未发现糖肽类耐药的葡萄球菌.

Distribution of pathogenic bacteria in patients of injuries combined with infection after May 12 Wenchuan Earthquake and drug resistance thereof

Objective To investigate the distribution of pathogenic bacteria in the patients of injuries combined with infection after May 12 Wenchuan Earthquake and the drug resistance thereof. Methods Bacterial culture and identification were conducted on 139 clinical specimens from 108 patients with open injuries combined with infection. Drug-sensitive test was carried out by Kirby-Bauer method on the isolated strains. Results Ninety-six stains were isolated,79.86% of them were from the infected wound secretion and 58.33% were from thee department of orthopedics. The bacteria with high isolation rates included Acinetobacter spp. (20 strains),Enterobacter cloacae (20 strains),Escherichia coli ( 17 strains),and Staphylococcus spp. (13 strains). The isolated Gram negative bacteria showed lower resistance to imipenem,amikacin,and cefoperazone/sulbactam. Conclusion The Gram negative bacteria isolated from the wounds caused by earthquake show lower resistance to imipenem,amikacin,and cefoperazone/sulbactam. No Staphylococcus spp. is found resistant to glycopeptides.