Laparoscopy in the abdominal staging of melanoma |
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| Affiliation: | 1. Department of Maternal and Child Health and Urological Sciences, Sapienza University, Policlinico Umberto I, Rome, Italy;2. Centre Leon Bérard, Hesper lab, EA 7425, Université Claude Bernard Lyon Est, Lyon, France;3. Department of Gynecology and Obstetrics, Innsbruck Medical University, Innsbruck, Austria;4. Department of Gynecology and Gynecological Oncology, Evangelische Kliniken Essen-Mitte, Essen, Germany;5. National University Cancer Institute, Singapore, Singapore;6. Gystave Roussy Cancer Campus, Villejuif, France;7. Department of Obstetrics and Gynecology, Niigata University Graduate School of Medical and Dental Sciences, Japan;8. Department of Gynecologic Oncology, National Hospital Organization Shikoku Cancer Center, Japan;9. Medical Oncology, Department of Internal Medicine and Pediatrics, Ghent University Hospital, Ghent, Belgium;10. Fondazione Policlinico Universitario A Gemelli IRCCS, Rome, Italy;11. Department of Gynecologic Oncology and Reproductive Medicine, University of Texas MD Anderson Cancer Center, Houston, TX, USA;12. Medical Oncology, Canterbury Regional Cancer and Haematology Service, Christchurch, New Zealand;13. Department of Obstetrics and Gynecology, National Defense Medical College, Tokorozawa, Saitama, Japan;14. Centre hospitalier de l''Université de Montréal (CHUM), Institut du cancer de Montréal, Montréal, Canada;15. Gynecologic Oncology Unit, Hokkaido Ohno Memorial Hospital, Sapporo, Japan;p. Department of Gynecology and Obstetrics, Carl-Gustav-Carus University, TU Dresden, Dresden, Germany on behalf of the AGO-Ovar, Germany;q. Institute of Obstetrics and Gynecology, Clinical Center, University of Debrecen, Debrecen, Hungary;r. Carmel Medical Center, Affiliated to the Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel;s. Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea;t. Department of Gynecology and Obstetrics, Ribeirao Preto Medical School, University of Sao Paulo, Brazil;u. Department of Obstetrics and Gynecology, Mayo Clinic, Rochester, MN, USA;v. Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, NeJoan & Sanford I. Weill Medical College of Cornell University, New York, NY, USA;w. University Hospital Leuven, Leuven, Belgium;x. Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore; Cancer Science Institute, National University of Singapore, Singapore;y. Department of Oncology, University College London Hospitals NHS Foundation Trust, London, UK;z. Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, Italy;11. Gynecologic Oncology Program, European Institute of Oncology, IRCCS, Milan and University of Milan-Bicocca, Milan, Italy;12. Department of Urology and Gynecology, Istituto Nazionale Tumori IRCCS Fondazione G. Pascale, Napoli, Italy;13. Arizona Oncology (US Oncology Network), University of Arizona, Creighton University, Phoenix, USA |
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| Abstract: | ![]()
A retrospective study on laparoscopic results in the abdominal staging of 297 patients with melanoma, is reported.In 195 (99.3%) of patients, laparoscopy was technically feasible, and in 10% the clinical stage was changed on the basis of the findings.In 34% of patients with metastasis of the liver and peritoneum, the tumor had a diameter of under 1 cm and therefore was not detectable with non-invasive techniques.In the light of these results laparoscopy is advisable in patients with Stage I melanoma at a high risk of metastatization (Clark IV–V; Breslow 0.76 mm) and in Stage II patients. In Stage III patients, laparoscopy seems indicated for an evaluation of the efficacy of systemic treatment. |
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