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Regression of pulmonary MALT lymphoma after treatment with rituximab
Authors:Chong Elise A  Svoboda Jakub  Cherian Sindhu  Andreadis Charalambos  Downs Lisa H  Zhuang Hongming  Alavi Abass  Tsai Donald E  Schuster Stephen J
Affiliation: a Hematology-Oncology Division, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvaniab Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvaniac Center for Functional Imaging, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania
Abstract:We describe a patient with extranodal (pulmonary) marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) who was refractory to treatment with cytotoxic chemotherapy. After a single four-week course of rituximab she had significant regression of pulmonary lesions and remains progression free 19 months after finishing her treatment. This case report demonstrates the potential efficacy of rituximab as a single therapeutic agent in patients with pulmonary MALT lymphoma.
Keywords:Rituximab  non-Hodgkin's lymphoma  MALT  marginal zone lymphoma
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