82例多发性硬化的临床与MRI分析

目的提高对多发性硬化的诊断水平。方法回顾性分析82例诊断明确多发性硬化(MS)患者的临床与磁共振成像(MRI)资料。结果MS好发于青壮年(84.0%),平均发病年龄(32.4±9.9)岁,女性发病率高于男性(1.6∶1),常见临床症状为肢体无力79.3%、感觉障碍39.0%、视力障碍31.7%、语言障碍29.3%和精神障碍14.6%等。MS病灶可仅位于脑内或仅位于脊髓内;或脑与脊髓和胼胝体。病灶多呈斑片状;在T1加权像上可为低、稍低或等信号,在T2加权像上多为高信号。结论结合临床与MRI表现可提高对MS诊断的准确性。

Analysis of MRI and Clinical Features In 82 Patients with Multiple Sclerosis

Objective To improve the diagnosis level of multiple sclerosis.Methods The clinical and MRI appearances of 82 clinically definitive MS were analyzed retrospectively,and the features of this disease were summarized.Results MS was commeonly seen in middle aged(32.4±9.9)people(84.0%).The rate of this desease in female is higher than the male(1.6∶1).The common clinical symptoms included weakness in limbs 79.3%,abnormal in sense 39.0%,dysfunction of eyesight 31.7%,language barrier 29.3% and psychogenia 14.6% etc.The locations of MS lesions were merely in the brain or only in the spinal cord or in brain,spinal cord patchy;They were showed as low,slightly low or middle signal intensity in T1 weighted images and high signal intensith in T2 weighted images.Conclusion The diagnostic accurary of diagnosis of MS could be improved by combining clinical and MRI features.