早产儿视网膜病相关危险因素的探讨

目的　探讨早产儿视网膜病 (ROP)发生的相关危险因素。　方法　以 13 5例早产儿患儿为研究对象 ,对胎龄、性别、出生体重、吸氧时间、吸氧浓度、肺透明膜病、Apgar评分、颅内出血、支气管肺发育不良、反复呼吸暂停、动脉导管开放、眼底等进行检查。同时用单因素 χ2 检验和多因素logistic回归分析筛选和判定早产儿ROP发生的危险因素。　结果　 13 5例中有 2 8例合并ROP ,占2 0 .7% (2 8/ 13 5)。经logistic回归分析 ,发现吸氧浓度、吸氧时间、出生体重、胎龄与早产儿ROP的发生有显著相关性 (r =0 .451,P <0 .0 5)。　结论　吸氧浓度、吸氧时间、出生体重、胎龄为早产儿ROP发生的重要危险因素 ,建议对所有早产儿常规行眼底检查 ,重视并针对其危险因素加以预防

Clinical Study on the Related Risk Factors for Retinopathy of Prematurity

ObjectiveTo assess the related risk factors of r etinopathy of prematurity. Methods Potential related risk factors of ROP, such as age, sex, birth weight, FiO 2, duration of inspiring ox ygen, hyaline membrane dzsease (HMD), Apgar score, intracranial hemorrhage(ICH) , recurrent apnea, broncho pulmonary dysplasia (BPD), patent ductus arteriosus ( PDA) were studied prospectively by univariate analysis and Logistic regression a nalysis in 135 preterm infants.ResultsROP was present in 28 of 135 subjects (20.7%). Logistic regression analysis revealed that age, birth w eight, FiO 2 and duration of inspiring oxygen were associated with ROP(r=0.45 1, P<0.05). ConclusionAge, birth weight, FiO 2 and durati on of inspiring oxygen are important risk factors related to ROP,more attention should be paid to prevent ROP.