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克心痛滴鼻剂对心肌缺血大鼠影响的实验研究
引用本文:王华,王殿华,邵念方. 克心痛滴鼻剂对心肌缺血大鼠影响的实验研究[J]. 中国中医急症, 2000, 9(4): 170-171
作者姓名:王华  王殿华  邵念方
作者单位:山东中医药大学附属医院,济南,250012
摘    要:目的 研究克心精滴鼻剂对心肌缺血大鼠的影响。方法 对垂体后叶素及冰水应激法致心肌缺血大鼠作心电图、心肌酶、SOD、MDA及血液注这指标的观测。结果 克心痛滴鼻剂可改善心肌缺血大鼠心电图表现,降低LDH、CK及MDA的含量,升高SOD含量,并改善血液流变学指标。结论克心痛滴鼻剂可改善心肌供血,防治心肌损伤,提高抗氧化能力,降低血液粘稠度,增加心肌血流量,从而起到防治冠心病心绞痛的作用。

关 键 词:克心痛滴鼻剂 心肌缺血大鼠 心电图 药理 中药
文章编号:1004-745X(2000)04-0170-02
修稿时间:1999-05-14

Experimental Study on Effect of Kexintong Nose Drops in Treating Myocardial Ischemia of Rats
Wang Hua,Wang Dianhua The Affiliated Hospital of Shandong University of TCM,Jinan. Experimental Study on Effect of Kexintong Nose Drops in Treating Myocardial Ischemia of Rats[J]. Journal of Emergency in Traditional Chinese Medicine, 2000, 9(4): 170-171
Authors:Wang Hua  Wang Dianhua The Affiliated Hospital of Shandong University of TCM  Jinan
Abstract:To observe the effect of Kexintong(KXT) on myocardial ischemia rats. Methods:ECG,myocardial enzymes,SOD,MDA and indexes of hemorrheology of myocardial ischemia rats caused by pituitrin and ice water stress reaction were detected.Results:KXT improved ECG ischemic findings,decreased the contents of LDH,CK and MDA,increased SOD and improved indexes of hemorrheology.Conclusion:KXT can improve myocardial blood supply,protect myocardial injury,raise antioxidation ability,lower blood viscosity and increase myocardial volume of blood flow.
Keywords:Kexintong nose drops   Myocardial ischemia rats   ECG   Myocardial enzymes   Antioxidation   Hemorrheology  
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