老年精神分裂症患者的认知功能研究

目的 探讨老年精神分裂症患者认知功能损害的范围和特点。方法 采用世界卫生组织老年认知功能评价成套神经心理测验(WHO-BCAI)、简易智能状态检查(MMSE)、日常生活量表(ADL)作为主要工具,对老年精神分裂症患者和正常老人进行测试。结果 老年精神分裂症组35例,男19例,女16例,平均年龄(63.24±6.5)岁。正常对照组83例,男42例,女41例,平均年龄(65.9±5.9)岁。MMSE平均总分,老年精神分裂症组(24.9±4.2)分,正常为(28.7±1.1)分;老年精神分裂症组ADL平均总分(27.1±8.1)分,正常组(20.3±1.2)分;WHO-BCAI测验结果显示,两组在7项听觉词汇学习测验、4项语言能力测验、4项视觉辨认测验、5项注销测验、2项连线测验、分类测验、精神运动测验和空间结构测验分别具有显著性差异(P<0.05)。结论 老年精神分裂症患者认知功能有明显障碍,并且范围广泛。

Cognitive function of elderly schizophrenics

Objectives: To study the characteristics and range of cognitive function on the elderly schizophrenia. Method: 35 elderly schizophrenic and 83 normal controls were assessed mainly by the World Health Organization battery of cognitive assessment instruments for elderly (WHO-BCAI) > mini-mental state examination (MMSE) and Activity of Daily Living scale (ADD. Results: The elderly schizophrenic patients performed significantly worse than normal controls on all the tests of MMSE, ADL (P<0. 01) and almost all the sub-tests of WHO-BCAI including verbal learning, language capability, visual recognizing, canceling, trail making, sorting, mental activity and spatial construction (P<0. 05). Conclusion: Cognitive impairment is markable and widespread in elderly schizophrenics.