| 苦瓜水溶性部位化学成分的研究 |
| |
| 引用本文： | 田宝泉,杨益平,何直升,叶阳. 苦瓜水溶性部位化学成分的研究[J]. 中草药, 2005, 36(5): 657-658 |
| |
| 作者姓名： | 田宝泉 杨益平 何直升 叶阳 |
| |
| 作者单位： | 中国科学院上生命科学院药物研究所,新药研究国家重点实验室,上海,200031 |
| |
| 摘 要： | ![]()
目的为揭示苦瓜M om ord ica charantia生理活性的化学物质基础,对其水溶性部位的化学成分进行了研究。方法经聚酰胺、大孔树脂、硅胶、RP-18和Sephadex LH-20反复柱色谱分得并通过波谱分析鉴定了7个化合物。结果分别为:1,2,3,4-四氢-1-甲基-β-咔啉-3-羧酸(1,2,3,4-tetrahydro-1-m ethy l--βcarbo line-3-carboxy licac id,Ⅰ)、腺苷(adenos ine,Ⅱ)、核黄素(riboflav ine,Ⅲ)、苦瓜苷A(m om ord icos ide A,Ⅳ)、苯丙氨酸(pheny la lan ine,Ⅴ)、甘露醇(m ann ito l,Ⅵ)、对羟基苯甲酸葡萄糖酯[1-(4-(hydroxybenzoy l)g lucose,Ⅶ]。结论化合物Ⅰ~Ⅲ及Ⅶ为首次从该植物中分得。化合物Ⅱ具有抗心率失常和心脏镇静活性。
|
| 关 键 词： | 苦瓜 化学成分 生物碱 |
| 文章编号： | 0253-2670(2005)05-0657-02 |
| 收稿时间： | 2004-07-04 |
Chemical constituents of water-soluble part of Momordica charantia |
| |
| TIAN Bao-quan,YANG Yi-ping,HE Zhi-sheng and YE Yang. Chemical constituents of water-soluble part of Momordica charantia[J]. Chinese Traditional and Herbal Drugs, 2005, 36(5): 657-658 |
| |
| Authors: | TIAN Bao-quan YANG Yi-ping HE Zhi-sheng YE Yang |
| |
| Affiliation: | State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China |
| |
| Abstract: | ![]()
|
| |
| Keywords: | Momordica charantia L. chemical constituents alkaloids |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《中草药》浏览原始摘要信息 |
|
点击此处可从《中草药》下载全文 |
|
