自体甲状腺组织与干细胞移植治疗甲状腺功能减退症的研究进展

不可逆性甲减患者需要终身服用甲状腺激素，对患者的日常工作和生活造成了很大的不便。随着近年来对自体甲状腺组织与干细胞移植研究的进展，有望解决甲减病人终身服药这一问题。自体甲状腺组织移植的动物实验以及人体试验均表明：甲状腺移植物不但能够存活，而且能够发挥作用。最新的胚胎干细胞（Embryonic stemcell，ESC）研究证明，ESC可以分化为甲状腺滤泡细胞。

Advance of Researches on Thyroid Tissues Autotransplantation and Embryonic Stem Cell Transplantation in Therapy of Hypothyroidism

Patients with irreversible hypothyroidism require lifelong levo-thyroxin(L-T4) replacement therapy, which makes them feel discomfortable. With the development of the thyroid tissues autotransplantation and embryonic stem cell (ESC), this would be a more physiological approach to the treatment of irreversible hypothyroidism. The animal experiments and human clinical trials on thyroid tissues autotransplantation have shown that the autograft can survive and function. The advanced researches have demonstrated ...