| 注射用头孢西丁钠与氟康唑氯化钠注射液配伍的稳定性 |
| |
| 引用本文： | 何培根,闵新文,郑芳,刘菁,朱雪松.注射用头孢西丁钠与氟康唑氯化钠注射液配伍的稳定性[J].医药导报,2011,30(4):518-520. |
| |
| 作者姓名： | 何培根 闵新文 郑芳 刘菁 朱雪松 |
| |
| 作者单位： | 1. 湖北医药学院附属东风医院,心血管内科,湖北十堰,442008
2. 湖北医药学院附属东风医院,药剂部,湖北十堰,442008 |
| |
| 摘 要： | 目的 考察室温(25±1)℃]下,注射用头孢西丁钠与氟康唑氯化钠注射液配伍的稳定性. 方法采用反相高效液相色谱法测定配伍液中头孢西丁钠与氟康唑0～6 h内的含量变化,并观察配伍液的外观及pH值. 结果 注射用头孢西丁钠与氟康唑氯化钠注射液4 h内配伍液外观、pH及含量均无明显变化. 结论 在室温下,注射用头孢西丁钠与氟康唑氯化钠注射液配伍后4 h内可使用.
|
| 关 键 词： | 头孢西丁钠 氟康唑氯化钠注射液 色谱法 高效液相 配伍 稳定性 |
| 收稿时间： | 2010-8-20 |
| 修稿时间： | 2010-10-9 |
Compatible Stability of Cefoxitin Sodium for Injection and Fluconazole and Sodium Chloride Injection |
| |
| HE Pei-gen,Min Xin-wen,ZHENG Fang,LIU Jing,ZHU Xue-song.Compatible Stability of Cefoxitin Sodium for Injection and Fluconazole and Sodium Chloride Injection[J].Herald of Medicine,2011,30(4):518-520. |
| |
| Authors: | HE Pei-gen Min Xin-wen ZHENG Fang LIU Jing ZHU Xue-song |
| |
| Institution: | HE Pei-gen1,Min Xin-wen1,ZHENG Fang2,LIU Jing2,ZHU Xue-song2 (1.Department of Cardiology,2.Department of Pharmacy,Dongfeng Hospital Affiliated with Huibei University of Medicine,Shiyan,Hubei 442008,China) |
| |
| Abstract: | Objective To study the compatible stability of cefoxitin sodium for injection and fluconazole and sodium chloride injection under ambient temperature. Methods The changes of contents of cefoxitin sodium and fluconazole were determined simultaneously by RP-HPLC,and those of appearance,pH value were observed within 6 hours. Results There were no significant changes in the contents,appearance and pH values of the compatible solution for 4h. Conclusion Cefoxitin sodium for injection is inadvisable to mix with f... |
| |
| Keywords: | Cefoxitin sodium Fluconazole and sodium chloride injection HPLC Compatibility Stability |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
| 点击此处可从《医药导报》浏览原始摘要信息 |
| 点击此处可从《医药导报》下载免费的PDF全文 |
|
