多普勒超声Tei指数评价尿毒症患者的左室功能

目的评价多普勒超声Tei指数估测尿毒症患者左室功能的价值。方法使用HP-5500型彩色超声诊断仪对30例尿毒症患者(尿毒症组)及35例正常人群(对照组)进行检测。检测指标包括左心腔室大小、左心室Tei指数、左室射血时间(ET)、左室射血分数(EF)、左室短轴缩短率(FS)、二尖瓣血流频谱E峰及A峰、E/A及左心室等容收缩时间(ICT)、左心室等容舒张时间(IRT)、主动脉射血时间(ET),并计算左心室Tei指数。结果尿毒症组左房内径(LAD)、左室舒张期内径(LVDd)、左室收缩期内径(LVDs)、室间隔(IVS)、左室后壁厚度(LVPW)均较正常对照组增大(P值均<0.01)。与对照组比较尿毒症组E峰明显增大(P<0.05),A峰明显增大(P<0.01),E/A无显著性差异(P>0.05);EF、FS无显著性差异(P>0.05);IRT延长(P<0.01),ET缩短(P<0.05),ICT无显著性差异(P>0.05)。经计算Tei指数明显延长(P<0.01)。结论Tei指数是评价尿毒症患者左心功能的简单、方便、有效的方法。

Estimating left ventricular function of patients with uremia by Tei index of Doppler echocardiogram

Objective To investigate the value of estimating left ventricular function of patients with uremia by Tei index of echocardiogram.Methods Thirty patients with uremia(uremia group)and 35 normal subjects(control group)were examined by color echocardiograph of HP-5500 type.The diameters of left atrium and ventricle,isovolumic relaxation time(IRT),isovolumic contraction time(ICT),ejection time(ET),ejection fraction(EF),fractional shortening(FS),peak E velocity,peak A velocity,E/A ratio were detected,and the Tei index was calculated.Results In uremia group,left atrial diameter(LAD),left ventricular diastolic diameter(LVDd),left ventricular systolic diameter(LVDs),interventricular septal thickness(IVS),thickness of left ventricular posterior wall(LVPW)were all enlarged compared with control group.There were no significant difference in EF and FS(all P>0.05)in two groups.Compared with control group,there were significant increases in peak E(P<0.05)and peak A(P<0.01)in uremia group,but E/A ratio remained unchanged(P>0.05)in two groups.Compared with control group,IRT was higher(P<0.01),and ET was lower(P<0.05),while ICT remained unaltered(P>0.05)in uremia group.The Tei index was obviously increased in uremia group.Conclusions The Tei index is valuable and easy for estimating the combined systolic and diastolic functions of left ventricle for patients with uremia.