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185例盐酸二氢埃托啡滥用者的调查
引用本文:曹永孝,孙燕玲,幸福,王耀,高文喜.185例盐酸二氢埃托啡滥用者的调查[J].中国药物依赖性杂志,1995(1).
作者姓名:曹永孝  孙燕玲  幸福  王耀  高文喜
作者单位:西安医科大学药学系,西安医科大学第一附属医院,西安市雁塔戒毒所
摘    要:对盐酸二氢埃托啡(dihydroetorphinehydrochloride,DHE)滥用者125例和阿片与DHE共同滥用60例进行了调查。发现滥用者绝大多数为中青年;平均年龄为27a;男多于女;文化程度低;工人、待业者、个体户占多数;好奇是初始滥用的主要原因,大多数滥用者初始滥用时不知道DHE能成瘾,单用DHE者,日滥用量9.6±s4.2片,滥用时间32±s2.3月,与阿片共同滥用者,DHE日用量21.4±s15.9片,滥用时间5.9±s5.2月。DHE的身体依赖发生率(32%)明显低于阿片(85.6%),DHE的戒断症状与阿片相似,但出现早、持续时间短、消失快、症状轻、易戒除。

关 键 词:二氢埃托啡,阿片,滥用,依赖

A SURVEY OF 185 DIHYDROETORPHINE HYDROCHLORIDE ABUSERS
Cao Yongxiao, Sun Yanling, Xing Fu, Wang Naiyao, Gao Wenxi.A SURVEY OF 185 DIHYDROETORPHINE HYDROCHLORIDE ABUSERS[J].Chinese Journal of Drug Dependence,1995(1).
Authors:Cao Yongxiao  Sun Yanling  Xing Fu  Wang Naiyao  Gao Wenxi
Institution:Cao Yongxiao1, Sun Yanling1, Xing Fu2, Wang Naiyao3, Gao Wenxi31
Abstract:ydrochloride(DHE) abusers and 60 DHE with opium abusers were investigated. It was found that most of the abusers were young and middle - aged; the average age was 27 years old; the number of male was more than that of female; their education level was low; workers, unemployed and self - employed labourers werein majority in occupation. The curiosity was the main cause of initial abuse. Most of theabusers did not know the addiction of DHE. In DHE abusers, the average time and amountof DHE abuse vere 3. 2 ± s 2. 3 months and 9. 6 ± s 4. 2 tablets·d-1, respectively. In poly drug abusers, the average time and the average amoumt of DHE abuse were 5. 9 ±s 5. 2months and 21. 4 ± s 15. 9 tablets· d-1. respectively. The physical dependence rate of DHE(32% )was markedly lower than that of opium (85. 6 % ). The abstinence syndromes of DHEoccurred earlier and lighter, disappeared faster, lasted shorter, and detoxified easier thanthose of opium.
Keywords:dihydroetorphine  opium  abuse  dependence
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