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甲磺酸左氧氟沙星对耐青霉素肺炎链球菌的体外抗菌活性
引用本文:于亮,李秀春,曹文华,王靖,王梅. 甲磺酸左氧氟沙星对耐青霉素肺炎链球菌的体外抗菌活性[J]. 中国抗生素杂志, 2003, 28(4): 240-241
作者姓名:于亮  李秀春  曹文华  王靖  王梅
作者单位:1. 泰山医学院附属医院,泰安,271000
2. 泰安市中心医院,泰安,271000
摘    要:
目的 观察甲磺酸左氧氮沙星对耐青霉素肺炎链球菌(PRSP)的药敏及疗效。方法 对6株临床分离的耐青霉素肺炎链球菌,采用E—test方法,测定甲磺酸左氧氮沙星等6种抗生素的抗菌活性。同时观察甲磺酸左氧氮沙星单药治疗取SP临床疗效及不良反应。结果6株取SP均为低耐药菌株,对甲磺酸左氧氮沙星敏感。6例患者经治疗后,5例痊愈,l例显效,无明显副反应发生。结论 甲磺酸左氧氮沙星可有效治疗耐青霉素肺炎链球菌性肺炎。

关 键 词:左氧氟沙星 耐青霉素肺炎链球菌 体外抗菌活性 药敏试验 疗效 甲磺酸左氧氟沙星
文章编号:1001-8689(2003)04-0240-02

In vitro antibacterial activity of levofloxacin against penicillin-resistant Streptococcus pneumoniae
Yu Liang ,Li Xiu-chun ,Cao Wen-Hua ,Wang Jing and Wang Mei. In vitro antibacterial activity of levofloxacin against penicillin-resistant Streptococcus pneumoniae[J]. Chinese Journal of Antibiotics, 2003, 28(4): 240-241
Authors:Yu Liang   Li Xiu-chun   Cao Wen-Hua   Wang Jing   Wang Mei
Affiliation:Yu Liang 1,Li Xiu-chun 1,Cao Wen-Hua 1,Wang Jing 1 and Wang Mei 2
Abstract:
Objective To investigate the antibacterial activity and clinical efficacy of levofloxacin against pencillin-resistant Streptococcus pneumoniae (PRSP). Methods E-test was used to examine the antibacterial activity of levofloxacin and others 5 antibiotics. The side effect and clinical efficacy were estimated after the patients were treated by levofloxacin. Results All 6 patients infected with PRSP were treated successfully by levofloxacin, 6 PRSP strains were susceptible to levofloxacin. Conclusion Levofloxacin could treat the PRSP infection effectively.
Keywords:Levofloxacin  Penicillin resistant Streptococcus pneumoniae (PRSP)  In vitro antibacterial activity
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