股骨头坏死患者生活质量临床研究

目的探讨股骨头坏死(ONFH)患者的生活质量及影响因素,为ONFH的治疗选择提供依据;探讨将生活质量作为其疗效评价的可行性。方法采用国际通用的SF-36量表对95例ONFH的住院患者和60例正常对照人群进行测量评分。155份量表的填写均为被调查者本人完成。95例ONFH患者按ARCO分期:Ⅰ期4例,Ⅱ期54例,Ⅲ期32例,Ⅳ期5例。界定Ⅰ～Ⅱ期为早期,Ⅲ～Ⅳ期为中晚期。将性别、年龄、职业、婚姻状况、文化程度、家庭收入等非疾病因素作为自变量,通过t检验、方差分析、多元逐步回归分析ONFH患者的生活质量及其影响因素。结果 ONFH组生活质量评分分别为躯体功能(PF)(69.42±16.16)分;躯体健康所致角色限制(RP)(24.11±34.91)分;躯体疼痛(BP)(67.02±14.36)分;总体健康(GH)(54.21±22.79)分;活力(VT)(65.42±22.65)分;社会功能(SF)(66.08±26.00)分;情绪问题所致角色限制(RE)(55.44±43.11)分;心理健康(MH)(65.73±18.96)分与正常组进行比较,差异有统计学意义(P0.01);早期和中晚期患者的PF、RP评分分别为(72.46±11.41)、(64.87±20.71)分和(19.74±31.60)、(38.16±37.10)分,差异有统计学意义(P0.05);非疾病因素对生存质量各维度均有影响,特别是文化程度和婚姻状况。结论生活质量的评价为ONFH治疗方法的选择提供了依据,把生活质量引入ONFH的疗效评价体系将更具有人性化。

Clinical Study on Quality of Life of Patients with Osteonecrosis of Femoral Head

Objective To study the quality of life (QOL) and the influencing factors among those patients with osteonecrosis of femoral head (ONFH),choose the method of treatment for ONFH to provide the basis and discuss the feasibility taking the evaluation of QOL as its effect appraisal.Methods According to the international general SF-36 measuring scale,95 ONFH hospital patients and 60 matched normal controls were checked up.In the SF-36 of collecting 95 ONFH patients,according to the classification system of ARCO,4...