| Abstract: | BACKGROUND: Stress shielding can lead to the failure of implant prostheses to repair bone defects, mainly due to the fact that the elastic modulus of the implant is greater than that of the surrounding bone tissues. OBJECTIVE: To explore methods for eliminating the stress shielding by analyzing the influence of the elastic modulus of the implanted prosthesis on the stress distribution. METHODS: The bone tissue models of experimental canine and human bone tissues were obtained by CT scanning, and then were optimized. The gradient assignment was performed to establish a reliable bone mechanics model, and the finite element simulation was performed after the combination with the implanted prosthesis. First, the finite element simulation of experimental canine and human bone tissues and the corresponding implanted prosthesis was performed to simulate the distribution of stress and displacement of prosthesis with different elastic moduli after prosthesis implantation. Second, the reasons for the stress shielding even with small elastic modulus differences were analyzed. The bone and implant prosthesis models were established, and a method for assigning material properties was established. Finally, the feasibility of the model and material property assignment method was verified, and the influence of the relationship between the elastic modulus of the implanted prosthesis and the elastic modulus of the bone on the formation of stress shielding was quantitatively analyzed by randomly selecting the stress points. RESULTS AND CONCLUSION: The mechanical properties of bone models of experimental canine and human bone tissues established by gradient assignment method are close to the actual bones. The finite element simulation mechanics test proved that the implantation of different elastic modulus had less effect on the relative displacement between the prosthesis itself and the surrounding bones. Moreover, quantifying the effects of elastic moduli on the stress distribution after implantation of the prosthesis into the bone will contribute to the research in the future. © 2023, Publishing House of Chinese Journal of Tissue Engineering Research. All rights reserved. |
