| 血液病与骨髓微血管研究进展 |
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| 引用本文： | 吴迪炯,周郁鸿,叶宝东,俞庆宏.血液病与骨髓微血管研究进展[J].中国实用内科杂志,2011(11):871-873. |
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| 作者姓名： | 吴迪炯 周郁鸿 叶宝东 俞庆宏 |
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| 作者单位： | 浙江省中医院血液科; |
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| 基金项目： | 浙江省中医药重大疾病科技创新平台科研专项(2009ZDJB01); 中医药行业科研专项(NO.201107001) |
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| 摘 要： | 骨髓微血管在血液系统疾病的发生发展中具有重要作用,其形成受多种调控因子的交互影响。目前在多种恶性血液病及非恶性血液病均发现存在血管生成的异常,骨髓微血管密度可作为判断疾病预后的重要指标,并在部分疾病中具有分层意义。通过给予相应的治疗,抑制或促进血管新生对提高疾病疗效具有重要意义,但部分疗效机制仍有待于深入探讨。
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| 关 键 词： | 骨髓微血管 血液病 调控因子 |
Advances in blood diseases and bone marrow microvessel |
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| WU Di-jiong,ZHOU Yu-hong,YE Bao-dong,YU Qing-hong.Advances in blood diseases and bone marrow microvessel[J].Chinese Journal of Practical Internal Medicine,2011(11):871-873. |
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| Authors: | WU Di-jiong ZHOU Yu-hong YE Bao-dong YU Qing-hong |
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| Institution: | WU Di-jiong,ZHOU Yu-hong,YE Bao-dong,YU Qing-hong.Zhejiang Hospital of Traditional Chinese Medicine,Hangzhou 310006,China |
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| Abstract: | Bone marrow microvessel plays an important role in the development and progression of hematologic diseases,and is regulated by a variety of regulatory factors.Since abnormal angiogenesis has been shown in a number of malignant and non-malignant hematologic diseases,microvessel density can be valuable as a prognostic indicator,and also as a stratifying factor in some of these diseases.In some cases,inhibiting or stimulating angiogenesis with certain treatment may seem important in improve the outcomes.Howeve... |
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| Keywords: | bone marrow microvessel hematologic diseases regulatory factor |
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