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口腔黏膜扁平苔藓癌变的诊断与综合治疗
引用本文:叶茂昌,马骏,王来平,李容新,李黎丽,曹浩. 口腔黏膜扁平苔藓癌变的诊断与综合治疗[J]. 中国口腔颌面外科杂志, 2011, 9(6): 518-520
作者姓名:叶茂昌  马骏  王来平  李容新  李黎丽  曹浩
作者单位:安徽医科大学附属省立医院口腔颌面头颈外科研究室,安徽合肥,230001
摘    要:
目的:探讨口腔黏膜扁平苔藓(OLP)癌变的诊断和以手术为主的综合治疗的效果。方法:对1998—2007年间收治的经临床初诊并经病理学证实的64例OLP癌变患者,从临床角度进行回顾性分析。为便于观察,均选择位于颊黏膜的患者,在PVP诱导化疗21d后选择根治性手术。结果:术后1、3年的生存率分别为87.50%和75.00%,局部复发11例(17.18%)。结论:探讨OLP癌变的诊断标准,解决了Krutchkoff等提出的不同意OLP癌变的3点质疑;OLP癌变治疗的重点在于综合治疗。

关 键 词:口腔扁平苔藓  癌变  鳞状细胞癌  综合治疗

The diagnosis and comprehensive treatment of oral lichen planus canceration
YE Mao-chang,MA Jun,WANG Lai-ping,LI Rong-xin,LI Li-li,CAO Hao. The diagnosis and comprehensive treatment of oral lichen planus canceration[J]. China Journal of Oral and Maxillofacial Surgery, 2011, 9(6): 518-520
Authors:YE Mao-chang  MA Jun  WANG Lai-ping  LI Rong-xin  LI Li-li  CAO Hao
Affiliation:YE Mao-chang,MA Jun,WANG Lai-ping,LI Rong-xin,LI Li-li,CAO Hao.(Department of Maxillofacial,Head and Neck Surgery,Provincial Hospital Affiliated to Anhui Medical University.Hefei 230001,Anhui Province,China)
Abstract:
PURPOSE: To discuss the diagnosis and comprehensive treatment based on operation and close observation of canceration of oral lichen planus(OLP).METHODS: Sixty-four patients with cancerous OLP were retrospectively analyzed,who were clinically diagnosed and pathologically confirmed to be OLP canceration from 1998 to 2007.Only patients who had buccal mucosal lesions were selected.After 21 days of PVP induction chemotherapy,all the patients underwent radical resection.RESULTS: The 1-and 3-year survival rate wa...
Keywords:Oral lichen planus  Canceration  Squamous cell carcinoma  Comprehensive treatment  
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