2009-2012年柳州市手足口病流行特征分析

目的分析柳州市2009--2012年手足口病分布特点和流行趋势，为制定防治对策提供科学依据。方法收集2009--2012年《疾病监测信息报告管理系统》报告的柳州市手足口病病例资料进行分析。结果2009-2012年柳州市共报告手足口病发病65735例，重症409例，死亡23例，报告发病率分别为205．54／10万、437．94／10万、456．81／10万和624．42／10万。发病主要集中在4—乇月；11个县（区）都有病例报告，男性发病率高于女性。5岁及以下儿童发病数较高，占95．68％；职业以散居儿童和幼托儿童为主，分别占67．79％和28．95％。实验室诊断病例366例，其中肠道病毒71（EV71）型阳性占71．86％，柯萨奇病毒A16（CoxA16）型阳性占9．29％，其他肠道病毒阳性占18．85％。结论柳州市手足口病疫情呈上升趋势，防治工作不容忽视，应强化多部门协作，加强社区散居儿童和托幼机构儿童手足口病的预防控制工作，以减少手足口病的暴发。

Analysis on epidemiological characteristics of hand-foot-mouth disease in Liuzhou City from 2009-2012

[ Objective ] To analyze the distribution characteristics and epidemiological trend of hand-foot-mouth disease （HFMD） in Liuzhou City from 2009-2012, provide a scientific basis for making prevention measures of HFMD. [ Methods] The data of HFMD cases in Liuzhou City from 2009-2012, which were reported by the Disease surveillance information management system, were ana-lyzed. [ Results] A total of 65 735 HFMD cases were reported in Liuzhou City from 2009-2012, and there were 409 severe cases and 23 death cases. The annual reported incidence rate was 205.54/lakh, 437.94/lakh, 456.81/lakh and 624.42/lakh, respectively. The peak season was April to June, and the cases were found in all 11 counties/districts. The incidence rate in males was higher than that in females. 95.68% of patients were children under 5 years old. The scattered children and nursery children accounted for 67.79% and 28.95% respectively. Among 366 cases confirmed by laboratory examination, 71.86% were positive for enterovir-us 71 （ EV71 ）, 9.29% were positive for coxsackie virus A16 （ CoxA16 ）, and 18.85% were positive for other enteric virus. [ Conclusion] The incidence rate of HFMD shows a rising trend in Liuzhou City, so HFMD prevention and control can not be ig-nored. It is necessary to strengthen multi-sector cooperation, and improve the prevention and control among scattered children and nursery children, to reduce HFMD outbreak.