SonoVue超声造影在肝良性占位病变诊断中的应用

目的探讨超声造影在肝良性占位病变诊断中的应用。方法30例肝良性占位病变患者经肘部静脉团注SonoVue。采用超声造影二次谐波成像技术,实时观察注射造影剂后病灶增强特征。结果经超声造影后,23个肝血管瘤动脉相均呈高回声增强,20个(87%)表现为周边向心型,2个(8.7%)为中央扩散型,1个(4.3%)为整体型增强特征,20个病灶在门脉相和延迟相仍为高回声增强,2个病灶渐变为等回声增强,1个病灶渐变为低回声增强。2个肝局灶性结节增生病灶在动脉相均呈中央扩散型增强,表现为轮辐状,门脉相及延迟相呈等回声增强。3个肝局部脂肪缺失病灶均显示动脉相无增强,门脉相及延迟相呈等回声。2个肝脓肿病灶动脉相周边无增强,延迟相病灶内呈低回声增强及无增强。结论SonoVue超声造影二次谐波成像技术能动态显示病灶增强特征,有助于肝良性占位病变的诊断及鉴别诊断。

Application of SonoVue contrast-enhanced ultrasound in benign focal hepatic lesions

Objective To investigate the application of SonoVue contrast-enhanced ultrasound and second harmonic imaging in benign focal hepatic lesions.Methods SonoVue was injected by bolus via peripheral vein of thirty patients with benign focal hepatic lesions.The technique of contrast-enhanced ultrasound and second harmonic imaging were used.The enhancement features of lesions were observed after injection of SonoVue.Results All hemangiomas revealed hyper-enhancement during arterial phase and 20(87%)of them showed periphery -to-center enhancement pattern,2(8.7%)showed center-to-periphery enhancement pattern,1(4.3%)revealed homogeneous enhancement pattern.20 lesions showed hyper-enhancement,2 showed iso- enhancement and 1 revealed hypo- enhancement at portal phase and late phase;2 focal nudolar hyperplasias showed center- to -periphery,central spoke wheel-shaped enhancement pattern during arterial phase.In the portal phase and late phase the lesion revealed iso-enhancement; 3 liver focal fatty sparing lesions had no enhancement in arterial phase.In the portal phase and late phase 3 lesions showed iso- enhancement; 2 hepatic abscesses showed periphery non-enhancement in arterial phase.In late phase 2 lesions showed internal hypo-enhancement and no enhancement.Conclusion The SonoVue contrast-enhanced ultrasound and second harmonic imaging reveals dynamic enhancement features of benign focal hepatic lesions,which is helpful to the diagnosis and differential diagnosis.