8例严重急性呼吸综合征死亡病例特点分析

目的总结8例严重急性呼吸综合征（severe acute respiratory syndrome，SARS）死亡病例临床特点，探讨应对突发传染病的教训与经验。方法总结病例的临床表现、影像资料、实验室资料及治疗措施，分析这些因素对预后的影响。结果SARS传染性强，潜伏期短，老年、妊娠及合并基础病患者预后不良。在早期尚未找到有效抗病毒药的情况下，早休息及合理对症治疗很重要。长期过量应用糖皮质激素易致血糖升高、二重感染等致死并发症。结论对新发传染病做到严密隔离、早休息、早期合理治疗，保护好高危人群至关重要。

Eight dead cases of severe acute respiratory syndrome

Objective To summarize clinical features of 8 dead eases of severe acute respiratory syndrome （SARS） and to discuss the lessons and experience in addressing emerging infectious diseases. Methods Clinical manifestations, imaging and labo- ratory data and treatment measures were summarized, and the influence of these factors on the prognosis was analyzed. Results SARS presented itself with high infectivity, short incubation period and poor prognosis in elderly patients, pregnant patients, or those with underlying diseases. Since there were no effective antiviral agents in the early stage of SARS, having sufficient rest as early as possible and undergoing proper symptomatic treatment played an important role. Prolonged use and overdosage of glucocortiocoids easily led to increased blood glucose levels, secondary infection and other deadly complications. Conclusion It is crucial to take such measures as strict isolation, sufficient and timely rest, proper treatment in the early stage and protection for high-risk group in addressing emerging infectious diseases.