连续肾替代抢救重症肾功能衰竭伴多器官衰竭40例临床研究

目的探讨重症。肾功能衰竭伴多器官衰竭（MODS）患者实施连续肾替代抢救治疗（CRRT）的临床效果。方法选取2011年6月至2013年6月连云港市第一人民医院肾功能衰竭患者40例，随机分为普通组和治疗组，普通组实施常规治疗，治疗组在常规治疗基础上实施CRRT治疗，对比两组治疗后尿素氮、血二氧化碳、血钾、肌酐、血氯、血钠等指标。结果普通组患者死亡10例（50．00％），治疗组患者死亡6例（30．00％），治疗组死亡率明显低于普通组（P〈0．05）；治疗组治疗后血肌酐、血尿素氮、血钾、血钠、血氯、血二氧化碳均有明显改善，优于普通组，差异有统计学意义（P〈0．05）。结论重症肾功能衰竭伴多器官衰竭患者实施连续肾替代抢救治疗的临床效果显著，可以有效提升抢救成功率。

Clinical research of continuous renal replacement rescue of severe renal failure with multi - organ failure 40 cases

Objective To investigate clinical results of the severe renal failure with multiple organ failure （MODS） res- cue for patients with continuous renal replacement therapy （CRRT）. Methods June 2011 - June 2013 Lianyungang the First People~ Hospital renal failure 40 patients were randomly divided into normal group and treatment group, the general implementation of the conventional treatment group, the treatment group based the conventional treatment on the implementation of CRRT two groups were compared after treatment urea nitrogen, blood carbon dioxide, potassium, cre- atinine, serum chloride, sodium and other indicators. Results 10 cases of death in patients of normal group （50. 00% ）, treatment group patients 6 deaths （30. 00% ）, the treatment group mortality was significantly lower than that of the normal group （P 〈 0. 05 ） ; After treatment, serum creatinine, blood urea nitrogen, potassium, sodium, ser- um chloride, blood carbon dioxide were significantly improved, better than that of the normal group, the difference was statistically significant （ P 〈 0. 05 ）. Conclusion Severe renal failure with multiple organ failure for patients with con- tinuous renal replacement salvage therapy has significant clinical effect, can effectively improve the success rate.