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Long-Term Outcome and Quality of Life After Continent Ileostomy
Authors:Gurel Nessar M.D.  Victor W. Fazio M.B.   M.S.  Paris Tekkis M.D.   F.R.C.S.  Jason Connor M.S.  James Wu M.D.   Ph.D.  Jane Bast B.S.   R.N.  Allison Borkowski B.A.  Conor P. Delaney M.B.B.Ch.  Feza H. Remzi M.D.
Affiliation:(1) Department of Colon and Rectal Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio, USA;(2) Department of Surgical Oncology and Technology, St. Mary's Hospital, Imperial College London, London, United Kingdom;(3) Department of Biostatistics and Epidemiology, The Cleveland Clinic Foundation, Cleveland, Ohio, USA;(4) Department of Colon and Rectal Surgery, A-30, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195, USA
Abstract:
Introduction This study was designed to evaluate long-term outcomes for patients undergoing Kock continent ileostomy, identify factors associated with adverse outcomes, and compare changes in quality of life after removal of the reservoir. Methods The records of all patients (n = 330) undergoing continent ileostomy at the Cleveland Clinic Foundation between 1974 and 2001 were reviewed. Patient-related, intraoperative, and postoperative factors were evaluated as predictor variables of long-term pouch survival. Quality of life was evaluated using the continent ileostomy surgery follow-up questionnaire and the Cleveland Global Quality of Life scale (n = 216). These were compared between patients with continent ileostomy (n = 181) and patients who underwent removal of the continent ileostomy and conversion to an end stoma (n = 35). Results The median patient follow-up was 11 (range, 1–27) years. The median revision-free pouch interval was 14 (95 percent confidence interval, 11–17) months. The 10-year and 20-year pouch survival was 87 and77 percent, respectively. Patients had an average of 3.7(range, 1–28) complications and 2.9 (range, 1–27) pouch revisions during follow-up. On multivariate analysis, Crohn's disease (hazard ratio = 4.5), female gender (hazard ratio = 2.4), fistula development (hazard ratio = 3), and body mass index (hazard ratio = 2.4 per 5 unit increase) were independent predictors of pouch failure. Quality of life measurements for patients with a continent ileostomy were higher on all scales in comparison with patients who had the Kock reservoir and then reverted to a Brooke ileostomy. Conclusions Despite the associated morbidity with continent ileostomy surgery, long-term results and quality of life were encouraging. Continent ileostomy may be offered as an attractive long-term option to select patients whose only alternative is an end ileostomy. Poster presentation at The Tripartite Colorectal Meeting, Dublin, Ireland, July 5 to 7, 2005.
Keywords:Continent ileostomy  Revision  Pouch failure
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