C反应蛋白测定在急性冠脉综合征中的临床意义

目的 探讨急性冠脉综合征（ACS）患者血浆C反应蛋白（CRP）含量变化及其对预后的影响。方法 采用免疫透射速率比法测定26例不稳定型的心绞痛患者（UAP组）和29例急性心肌梗死患者（AMI组）的CRP水平并测定肌酸激酶（CK），肌酶激酶同工酶（CK-MB），乳酸脱氢酶（LDH），同时选择30例体检正常者为对照组。结果 ACS患者CRP的水平和CK，CK-MBLDH呈显著正相关（P〈0．01），三组心脏事件发生率间差别有显著意义（P〈0.05）。结论 ACS患者CRP水平显著升高，是危险因素，可作为判断预后的预测指标。

The Clinic value of C-reactive protein Measurement in Patients with Acute Coronary Syndrome

Objective To discuss the content change of plasma C-reactive protein(CRP) and its influence to prognosis of the acute coronary syndrome(ACS), Methods CRP Level was detected by velocity scatter immune turhidimetry in 26 patients with unstable angina pectoris (UAP) and 29 patients with acute myocardial infarction(AMI). Creatine Kinase (CK), MB isoenzyme of creatine kinase(CK-MB), lactate dehydrogenase(LDH) were detected by enzyme technique, 30 persons of normal health examination were selected as a control group. Result CRP level in patients with ACS was positive correlativity with CK, CK-MB,LDH(P <0.01), The toal distribution of heart event incidence in three groups was different(P>0.05). Conclusion CRP level was significantly higher in patients with ACS. It is a dangerous factor and it is regarded as an indication for the prognosis.