| 哮喘中IL—5和IL—10基因表达及其相关性研究 |
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| 引用本文： | 罗百灵,吴鄂生.哮喘中IL—5和IL—10基因表达及其相关性研究[J].湖南医科大学学报,2000,25(2):99-102. |
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| 作者姓名： | 罗百灵 吴鄂生 |
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| 摘 要： | ３１只健康豚鼠分为哮喘组、地塞米松干预组及对照组。测定各组豚鼠肺泡灌洗液细胞成分，应用ＲＴ－ＰＣＲ方法检测支气管组织白细胞介素－５（ＩＬ－５）和白细胞介素－１０（ＩＬ－１０）ｍＲＮＡ表达强度。结果显示，哮喘组豚鼠肺泡灌反。ＩＬ－５ｍＲＮＡ表达与ＥＯＳ百分比呈正相关，而与ＩＬ－１０ｍＲＮＡ表达呈负相关。说明ＥＯＳ，ＩＬ－以正相关参与了哮喘发病。哮喘时ＩＬ－１０表达受抑制，这可能是炎症细胞因子ＩＬ－５
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| 关 键 词： | 哮喘 白细胞介素5 白细胞介素10 基因表达 |
Expression of interleukin-5 and interleukin-10 and their relationship in asthma] |
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| B L Luo,E S Wu,W F Qiu,Z H Hai.Expression of interleukin-5 and interleukin-10 and their relationship in asthma][J].Bulletin of Hunan Medical University,2000,25(2):99-102. |
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| Authors: | B L Luo E S Wu W F Qiu Z H Hai |
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| Institution: | Department of Internal Medicine, Xiangya Hospital, Hunan Medical University, Changsha 410008. |
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