| Institution: | 1. Department of Public Health and Primary Care, Faculty of Medicine and Health Sciences, Ghent University, C.Heymanslaan 10 - 4K3, 9000 Ghent, Belgium;2. Departments of Public Health Nutrition, Faculty of Public Health, Mulawarman University, Samarinda, East Kalimantan, Indonesia;3. Univ. Lille, Inserm, CHU Lille, CIC 1403 - Centre D''investigation Clinique, F-59000 Lille, France;4. Univ. Lille, Inserm, CHU Lille, U1286 - INFINITE – Institute for Translational Research in Inflammation, F-59000 Lille, France;5. GENUD (Growth, Exercise, Nutrition and Development) Research Group, Faculty of Health Science, University of Zaragoza, C/Pedro Cerbuna 12, 50009 Zaragoza, Spain;6. Instituto Agroalimentario de Aragón (IA2) and Instituto de Investigación Sanitaria de Aragón (IIS Aragón), Spain;7. Centro de Investigación Biomédica en Red de Fisiopatología de La Obesidad y Nutrición (CIBEROBN), Spain;8. Instituto de Salud Carlos III, Madrid, Spain;1. Department of Cardiology, Rigshospitalet, University Hospital, Copenhagen, Denmark;2. Department of Cardiology, Zealand University Hospital, Roskilde, Denmark;3. Novartis Healthcare, Denmark;4. I2minds, Aarhus, Denmark;5. Danish Institute for Health Services Research, Copenhagen, Denmark;1. Association for Cardiac Research, Rome, Italy;2. EA 4650, Signalisation, électrophysiologie et imagerie des lésions d''ischémie reperfusion myocardique, UNICAEN, 14000 Caen, France;3. Research Centre for Food and Nutrition, Council for Agricultural Research and Economics (CREA-AN), Rome, Italy;1. National Institute for Health Research Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, UK;2. Musculoskeletal Research Unit, Translational Health Sciences, Bristol Medical School, University of Bristol, Learning & Research Building (Level 1), Southmead Hospital, Bristol, UK;3. Central Finland Health Care District Hospital District, Department of Medicine, Finland District, Jyväskylä, Finland;4. Diabetes Research Centre, University of Leicester, Leicester General Hospital, Gwendolen Road, Leicester, LE5 4WP, UK;5. Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland;6. Institute of Clinical Medicine, Department of Medicine, University of Eastern Finland, Kuopio, Finland |
| Abstract: | Background and aims(Poly)phenols might contribute to prevent cardiovascular disease, but limited prospective studies exist among adolescents. This study aimed to evaluate within-subject longitudinal changes in (poly)phenols intakes and food group contributors while also exploring the association with metabolic syndrome risk (MetS) during 10 years of follow up in European adolescents becoming young adults.Methods and resultsIn 164 participants (58% girls, 13-18 y at baseline) from Ghent, Zaragoza and Lille, longitudinal data (2006–2016) on (poly)phenol intake was retrieved via 2 or 3 24 h recalls. Linear and logistic longitudinal regression tested the association of (poly)phenols intake (total and classes) with Mets risk or its components (waist-height-ratio, HDL cholesterol, LDL cholesterol, triglycerides, blood pressure and insulin resistance index), adjusted for age, sex, country and other nutrient intakes. The total (poly)phenols intake was 421 ± 107 mg/day (192 mg/1000 kcal/day) at baseline, while 610 ± 101 mg/day (311 mg/1000 kcal/day) at follow-up. The three major food sources for (poly)phenols were ‘chocolate’, ‘fruit and vegetable juices’, ‘cakes and biscuits’ during adolescence and ‘coffee’, ‘tea’ and ‘chocolate’ during adulthood. Phenolic acid intake was associated with less LDL increase over time, while stilbene intake with a steeper increase in triglycerides over time.ConclusionsDifferences in major (poly)phenols contributors over time were partially explained by age-specific dietary changes like increased coffee and tea during adulthood. Some significant (poly)phenols-MetS associations might argue for nutrition-based disease prevention during adolescence, especially since adolescents had low (poly)phenols intake. |
