急诊内镜套扎联合奥曲肽治疗肝硬化合并食管静脉曲张出血的疗效分析

目的]探讨急诊内镜套扎联合奥曲肽治疗肝硬化合并食管静脉曲张出血的疗效.方法]将121例肝硬化合并食管静脉曲张出血患者分为观察组（n=61）与对照组（n=60）,观察组患者接受急诊内镜套扎联合奥曲肽治疗,对照组患者接受奥曲肽治疗.结果]①观察组止血成功率显著高于对照组（P＜0.05）,早期再出血发生率显著低于对照组（P＜0.05）;两组患者病死率相比差异无统计学意义（P＞0.05）.②观察组止血时间、奥曲肽治疗天数、输血量、住院时间显著少于对照组（均P＜0.05）.③观察组不良反应发生率显著高于对照组（P＜0.05）.结论]急诊内镜套扎联合奥曲肽治疗肝硬化合并食管静脉曲张出血的患者的效果显著.

Analysis of the Efficacy of Emergency Endoscopic Variceal Ligation Combined with Octreotide for the Treatment of Liver Cirrhosis Complicated with Esophageal Variceal Bleeding

Objective] To explore the efficacy of emergency endoscopic variceal ligation combined with octreotide for the treatment of liver cirrhosis complicated with esophageal variceal bleeding. Methods] Totally 121 cases of liver cirrho-sis complicated with esophageal variceal bleeding were divided into observation group（ n = 61 ） and control group （ n=60）. The observation group received emergency endoscopic variceal ligation combined with octreotide, while the control group received octreotide. Results] The success rate of hemostasis in observation group was significantly higher than that in control group（ P〈0.05）, and the incidence rate of early rebleeding was significantly lower than that of control group （ P〈0.05）. There was no significant difference in the mortality rate between 2 groups（ P〉0.05）. The hemostasis time, days of using octreotide, volume of blood transfusion and length of stay in observation group were significantly less than those in control group（all P 〈0. 05）. The incidence rate of adverse reaction in observation group was significantly higher than that in control group（ P 〈0.05）. Conclusion] Emergency endoscopic variceal ligation combined with oct-reotide for the treatment of liver cirrhosis complicated with esophageal variceal bleeding is of significant efficacy.