QLQ-BR23和EORTC QLQ-C30测量康复锻炼对乳腺癌患者生命质量的影响

 目的  探讨康复期锻炼对乳腺癌患者生命质量的影响。方法  采用横断面研究方法,整群抽样上海癌症康复俱乐部1 956名女性乳腺癌康复期患者进行问卷调查,调查问卷采用欧洲癌症研究与治疗组织生命质量量表(quality of life questionnaire core 30,EORTC QLQ-C30)和乳腺癌生存质量量表(quality of life questionnaire breast cancer module 23,QLQ-BR23)。结果  QLQ-BR23的信度和效度分别为0.898和0.904,EORTC QLQ-C30的信度和效度分别为0.988和0.989;对于QLQ-BR23量表,康复锻炼、锻炼次数和生命质量均无统计学意义。但是参与康复锻炼和锻炼次数≥5次/周患者的功能症状总得分高于未参加康复锻炼和康复锻炼＜5次/周患者。对于EORTC QLQ-C30量表,通过调整社会人口学等因素,参加康复锻炼患者的躯体功能及总体健康状况得分均显著高于不参加体育锻炼患者(P<0.05,PAdjusted<0.05);康复锻炼≥5次/周患者的5个功能维度及总体健康状况得分均高于康复锻炼＜5次/周患者,但只有躯体功能差异有统计学意义(P<0.05,PAdjusted<0.05)。结论  参加康复锻炼的乳腺癌患者总体生命质量高于未参加锻炼者,康复锻炼对提高乳腺癌患者的生命质量有积极影响。

QLQ-BR23 and EORTC QLQ-C30 for the measurement of the impact of rehabilitation exercise on quality of life in breast cancer patients

Objective  To investigate the associations between rehabilitation exercise and quality of life in breast cancer patients.Methods  A cross-sectional study and cluster sampling was conducted among 1 956 breast cancer patients in convalescence stage.Data were collected using a questionnaire according to scores of quality of life questionnaire beast cancer module 23 (QLQ-BR23) and quality of life questionnaire-core 30 (EORTC QLQ-C30).Results  The reliability and validity of QLQ-BR23 were 0.898 and 0.904. The reliability and validity of EORTC QLQ-C30 were 0.988 and 0.989. ForQLQ-BR23 scale,rehabilitation exercise and exercise frequency had no statistical significance with quality of lifeHowerer,the total scores of patients attending rehabilitation exercise more than or equal to 5 times/week were higher than those who did exercise less than 5 times/week.For EORTC QLQ-C30,after adjusted social demography factors,total scores of patients attended rehabilitation exercise reported higher global health functioning scores than those who did not take exercise (P<0.05,P Adjusted<0.5)． Breast cancer patients who did exercise more than or equal to 5 times/week reported higher QLQ-C30 total scores than those who did exercise less than 5 times/week,but only health functioning scores showed statistical difference (P<0.05,P Adjusted<0.5)Conclusions  The overall quality of life of breast cancer patients attend rehabilitation exercise is better than those who do not attend the exercises. The present study indicates that rehabilitation exercise improves the quality of life of breast cancer patients.