|
|||||
|
|
| 133例智力低下患儿细胞遗传学研究 | |
| 引用本文： | 马宁,杨晓,朱丽娜,王春枝. 133例智力低下患儿细胞遗传学研究[J]. 中国优生与遗传杂志, 2012, 0(8): 62-63 |
| 作者姓名： | 马宁 杨晓 朱丽娜 王春枝 |
| 作者单位： | 北京军区总医院附属八一儿童医院临床遗传学中心 |
| 摘 要： | 目的探讨智力低下患儿与染色体异常的关系。方法常规外周血染色体核型分析。结果 133例患儿中共检出染色体异常74例,异常检出率55.6%。其中常染色体数目异常62例,结构异常9例;性染色体数目异常2例,结构异常1例,结论染色体异常是导致儿童智力低下的重要原因,对此类患儿进行染色体核型分析很有必要。 |
| 关 键 词： | 智力低下 染色体异常 儿童 |
Chromosome analysis in 133 children with congenital mental retardation |
|
| MA-Ning,YANG Xiao,ZHU Li-Na,WANG Chun-Zhi. Chromosome analysis in 133 children with congenital mental retardation[J]. Chinese Journal of Birth Health & Heredity, 2012, 0(8): 62-63 | |
| Authors: | MA-Ning YANG Xiao ZHU Li-Na WANG Chun-Zhi |
| Affiliation: | .(Clinical Genetics Center of Bayi Children′s Hospital Affiliated to Beijing Military General Hospital,100700,Beijing,China) |
| Abstract: | Objective: To explore the chromosome karyotypes in children with mental retardation.Methods: The peripheral blood lymphocytes from 133 children with congenital mental retardation were cultured and analysed by the G-band technique.Results: Of the 133 cases,74cases(55.6%) showed chromosome abnormalities.The number of autosomal abnormalities were found in 62 cases and Autosomal structural chromosome abnormalities were found in 9 cases.the number of sex chromosome abnormalities in 2 cases and sex chromosome structural abnormalities in 1cases.Conclusions: Chromosome abnormalities may be important cytogenetic factors for congenital mental retardation.Cytogenetic chromosome karyotypic analysis is an important method for congenital mental retardation child. |
| Keywords: | Mental retardation Chromosome karyotype Child |
| 本文献已被 CNKI 维普 等数据库收录！ | |