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| 乙肝肝硬化患者血清HBV DNA与透明质酸的关系 | |
| 引用本文： | 李红艺,董忠,马红. 乙肝肝硬化患者血清HBV DNA与透明质酸的关系[J]. 中华实验和临床病毒学杂志, 2007, 21(3): 256-257 |
| 作者姓名： | 李红艺 董忠 马红 |
| 作者单位： | 首都医科大学附属北京友谊医院肝病中心,100050 |
| 摘 要： | 目的研究乙肝肝硬化患者血清HBV DNA水平和血清透明质酸的关系。方法临床确诊为乙肝肝硬化的62例患者,采用荧光定量PCR检测血清HBV DNA水平,放射免疫法检测血清透明质酸,对血清HBV DNA水平和透明质酸的关系进行研究分析。结果乙肝肝硬化患者的血清透明质酸水平显著升高,随Child分级的加重血清透明质酸也呈增高趋势(P<0.05),但与血清HBV DNA水平差异无统计学意义(P>0.05)。结论乙肝肝硬化患者的血清HBV DNA和肝硬化的程度及血清透明质酸水平无显著相关性。 |
| 关 键 词： | 肝硬化 肝炎病毒 乙型 透明质酸 |
| 收稿时间： | 2007-03-18 |
Relationship between serum HBV DNA levels and serum hyaluronic acid levels in hepatitis B cirrhosis patients |
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| LI Hong-yi,DONG Zhong,MA Hong. Relationship between serum HBV DNA levels and serum hyaluronic acid levels in hepatitis B cirrhosis patients[J]. Chinese journal of experimental and clinical virology, 2007, 21(3): 256-257 | |
| Authors: | LI Hong-yi DONG Zhong MA Hong |
| Affiliation: | Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing, China. |
| Abstract: | Objective To probe the relationship between serum HBV DNA levels and serum hyaluronic acid(HA)levels in hepatitis B cirrhosis patients.Methods Of 62 patients diagnosed with hepatitis B cirrhosis serum HBV DNA was determined by fluorescent quantitative PCR.Serum HA was determined by radioimmunity assay.The relationship between serum HBV DNA levels and serum HA levels was probed.Results Serum HA of hepatitis B cirrhosis patients increased significantly and increased with the Child grade ascending(P<0.05).But serum HA levels had no significant correlation with serum HBV DNA levels(P>0.05).Conclusions Serum HBV DNA levels had no significant correlation with liver cirrhosis grades and serum HA levels in hepatitis B cirrhosis patients. |
| Keywords: | Iiver cirrhosis Hepatitis B virus Hyaluronic acid |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |