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| 肺耐药相关蛋白的研究进展 | |
| 引用本文： | 唐海桦,梁钢. 肺耐药相关蛋白的研究进展[J]. 医学综述, 2008, 14(3): 462-464 |
| 作者姓名： | 唐海桦 梁钢 |
| 作者单位： | 广西医科大学药学院药理教研室,南宁,530021 |
| 基金项目： | 广西地方性高发疾病重点实验室科学基金 |
| 摘 要： | 肿瘤多药耐药(MDR)是近年来肿瘤治疗研究的困扰之一,其产生机制非常错综复杂。随着对非P-糖蛋白介导MDR机制研究的不断深入,肺耐药相关蛋白(LRP)被证实在MDR中发挥着重要作用,有望成为一种新的治疗靶点。本文就LRP的生理特性、分布、耐药机制、检测手段、临床意义及其介导的MDR逆转做一简要综述。 |
| 关 键 词： | 多药耐药 肺耐药相关蛋白 逆转 |
| 文章编号： | 1006-2084（2008）03-0462-03 |
| 收稿时间： | 2007-09-10 |
| 修稿时间： | 2007-11-04 |
Advance of Lung Resistance-Related Protein |
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| TANG Hai-hua,LIANG Gang. Advance of Lung Resistance-Related Protein[J]. Medical Recapitulate, 2008, 14(3): 462-464 | |
| Authors: | TANG Hai-hua LIANG Gang |
| Affiliation: | TANG Hai-hua,LIANG Gang.(Department of Pharmacology,College of Pharmacy,Guangxi Medical University,Nanning 530021,China) |
| Abstract: | Multidrug resistance (MDR) is one of curses on oncotherapy study in recent years,the mechanisms of which are intricate extremely.A kind of multidrug resistance,lung resistance-related protein(LRP),were demonstrated to play an important role in MDR,which might be a new therapeutic target.In this article,the physiological nature,distribution,mechanism of drug resistance,the way of examination,the clinic significance and the reverse of multidrug resistance were briefly summarized. |
| Keywords: | Mtdtidrug resistance Lung resistance-related protein Reverse |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |