| 缬沙坦对心力衰竭患者心功能及QT离散度的影响 |
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| 引用本文： | 刘向儒,谭小军,张晓红,陈小亮,王仲华. 缬沙坦对心力衰竭患者心功能及QT离散度的影响[J]. 医药导报, 2003, 22(3): 156-158 |
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| 作者姓名： | 刘向儒 谭小军 张晓红 陈小亮 王仲华 |
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| 作者单位： | 湖南省郴州市第一人民医院心内科,423000 |
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| 摘 要： | 目的：观察缬沙坦对扩张型心肌病(DCM)心力衰竭(心衰)患者心功能及QT离散度(QTd)的影响.方法：DCM心衰患者84例,分为两组.治疗组44例,用缬沙坦80 mg,qd,对照组40例,接受常规(包括卡托普利25 mg,bid)治疗,疗程均为1个月.两组治疗前后观察临床疗效,检查心脏彩色B超,同时检查心电图测量QTd.比较两组以上三方面变化.结果：治疗组在临床疗效、心功能变化及QTd变化方面明显优于对照组.结论：缬沙坦治疗DCM明显优于卡托普利,对于DCM心衰的患者,应早期尽快使用缬沙坦,这对于阻止心肌的进一步损伤,保护心脏功能,减少心律失常将起到有益的作用.
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| 关 键 词： | 缬沙坦；心肌病 扩张型；QT离散度；力力衰竭 |
| 文章编号： | 1004-0781(2003)03-0156-03 |
| 修稿时间： | 2002-09-17 |
Effect of Valsartan on Heart Function and QT Dispersion in Patients with Heart Failure |
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| LIU Xiang ru,TAN Xiao jun,ZHANG Xiao hong,CHEN Xiao liang,WANG Zhong hua. Effect of Valsartan on Heart Function and QT Dispersion in Patients with Heart Failure[J]. Herald of Medicine, 2003, 22(3): 156-158 |
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| Authors: | LIU Xiang ru TAN Xiao jun ZHANG Xiao hong CHEN Xiao liang WANG Zhong hua |
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| Abstract: | Objective:To evaluate the effect of valsartan on QT dispersion and heart function in patients with dilated cardiomyopathy(DCM). Methods:Among the 84 DCM patients, 44 underwent valsartan treatment and 40 underwent captopril treatment. The QTd and heart function were observed and compared after 2 weeks. Results:The treatment group was superior to the control group in therapeutic effect, changes of heart function and changes of QTd. Conclusion:valsartan in treating DCM is batter than captopril in improving function of the left ventricle and reducing the occurrence of arrhythmias. |
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| Keywords: | Valsartan Dilated cardiomyopathy QT dispersion Heart failure |
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