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VEGF和PEDF在增殖性糖尿病视网膜病变中的研究进展
引用本文:陈小红,王云鹏,陈梅珠.VEGF和PEDF在增殖性糖尿病视网膜病变中的研究进展[J].国际眼科杂志,2015,15(1):55-57.
作者姓名:陈小红  王云鹏  陈梅珠
作者单位:南京军区福州总医院厦门大学附属东方医院 福建医科大学福总临床医学院, 中国福建省福州市,350025
基金项目:福建省科技厅重点项目(No.2012Y0055)
摘    要:增殖性糖尿病视网膜病变( proliferative diabetic retinopathy,PDR)是一种以眼内新生血管形成为特征的糖尿病并发症。眼内新生血管的形成是当今世界主要致盲原因之一。血管内皮生长因子( vascular endothelial growth factor,VEGF)与色素上皮衍生因子( pigment epithelium-derived factor,PEDF)作为眼内新生血管形成最主要的细胞因子,近年来成为研究热点。本文就VEGF和PEDF在PDR中的研究进展进行综述。

关 键 词:血管内皮生长因子  色素上皮生长因子  增殖性糖尿病视网膜病变
收稿时间:9/6/2014 12:00:00 AM
修稿时间:2014/12/19 0:00:00

Recent progress in the investigation of VEGF and PEDF of proliferative diabetic retinopathy
Xiao-Hong Chen,Yun-Peng Wang and Mei-Zhu Chen.Recent progress in the investigation of VEGF and PEDF of proliferative diabetic retinopathy[J].International Journal of Ophthalmology,2015,15(1):55-57.
Authors:Xiao-Hong Chen  Yun-Peng Wang and Mei-Zhu Chen
Institution:Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, Fujian Province, China;Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, Fujian Province, China;Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, Fujian Province, China
Abstract:Proliferative diabetic retinopathy(PDR)is a group of disease characterized by neovascular disease complication of diabetes mellitus. Neovascular diseases of eye are one of the major causes of blindness of the world. Recent studies showed that vascular endothelial growth factor(VEGF)and pigment epithelium-derived factor(PEDF)are now accepted as the key cytokine in the development of diabetic retinopathy. Recent progress in the investigation of VEGF and PEDF of PDR are summarized in this review.
Keywords:vascular endothelial growth factor  pigment epithelium-derived factor  proliferative diabetic retinopathy
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