回肠浆肌层膀胱扩大术的实验研究

为防止膀胱扩大术后单层回肠浆肌层挛缩及肠粘膜再生，将１８只犬分为３组进行了回肠浆肌层膀胱扩大术的实验研究。术后临床观察半年并行尿流动力学、病理学和血生化检查。结果发现：应用去粘膜技术可完全去除肠粘膜而无再生；双层回肠浆肌层材料及保留膀胱粘膜可较好地克服术后膀胱挛缩。

BLADDER AUGMENTATION USING SEROMUSCULAR SEGMENT OF ILEUM:AN EXPERIMENTAL STUDY

An animal experiment was designed to resolve the regeneration of bowel mucosa and the contracture of the patch after bladder augmentation utilizing seromuscular segment of intestine.Eighteen mongrel dogs were divided into three groups and underwent augmentation using deepithelialized segment of ileum.Of 18 dogs 13 survived and were observed clinically until sacrifice at 6 months postoperatively.Blood biochemistry studies,cystometries,retrograde cystograms and etc.were performed on the all surviving dogs.The bladder and their seromuscular patches were examined grossly and histologically.It was found that Chen's procedure achieved complete demuscosation easily without the regeneration or the residue of bowel mucosa,and using 2 layer seromuscular patch and leaving bladder mucosa intact could even better prevent the patch from contracture.