2009年甲型H1N1流感的病原学及临床特征

2009年甲型H1N1流感暴发并在全世界范围内流行,相关问题也逐渐成为研究热点,据目前资料显示该病毒的HA基因衍生于1918年的流感病毒,而其他的基因片段包括了人、禽类及欧亚猪流感病毒.在临床表现上,甲型H1N1流感与季节性流感相似,目前,该病毒尚对NA抑制剂敏感.作为甲型H1N1流感的第一急救者,急诊医师应对该病的病原学、临床表现、流行病学、治疗及预防等各方面提高认知.

Characteristics of etiology and clinical manifestations of H1N1 in 2009

In 2009, a novel influenza virus A (H1N1) pandemic was found in the whole world.This virus has HA gene derived from the 1918 swine influenza virus and other genes from human, avian, and Eurasian swine influenza viruses.Clinically, it is similar to seasonal influenza.To date, with few exceptions, the 2009 HI NI virus remains susceptible to NA inhibitors (osehamivir and zanamivir).Today this disease has become the hottest issue which the clinicians work on.As emergency physicians,we are the first - responders to the illness.It is important to get to know the characteristics of the etiology and clinical issues of A HI NI virus and the influenza.