| Cardioprotective activity of alcoholic extract of Tinospora cordifolia （Willd.） Miers in calcium chloride-induced cardiac arrhythmia in rats |
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| 引用本文： | Ashish Kumar Sharma,Kunal Kishore,Divya Sharma,B.P Srinivasan,Shyam Sunder Agarwal,Ashok Sharma,Santosh Kumar Singh,Samir Gaur,Vijay Singh Jatav. Cardioprotective activity of alcoholic extract of Tinospora cordifolia （Willd.） Miers in calcium chloride-induced cardiac arrhythmia in rats[J]. 南京医科大学学报(英文版), 2011, 0(4): 280-286 |
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| 作者姓名： | Ashish Kumar Sharma Kunal Kishore Divya Sharma B.P Srinivasan Shyam Sunder Agarwal Ashok Sharma Santosh Kumar Singh Samir Gaur Vijay Singh Jatav |
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| 作者单位： | Department of Pharmacology;Gyan Vihar School of Pharmacy;Suresh Gyan Vihar University;Jagatpura;Jaipur (Rajasthan);India;Delhi Institute of Pharmaceutical Sciences & Research;Pushpvihar;Sector Ⅲ.New Delhi; |
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| 摘 要： | ![]()
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| 关 键 词： | 抗心律失常 乙醇提取物 氯化钙 大鼠 心脏 氯化物 酒精 迈尔 |
Cardioprotective activity of alcoholic extract of Tinospora cordifolia (Willd.) Miers in calcium chloride-induced cardiac arrhythmia in rats |
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| Journal of Biomedical Research. Cardioprotective activity of alcoholic extract of Tinospora cordifolia (Willd.) Miers in calcium chloride-induced cardiac arrhythmia in rats[J]. Journal of Nanjing Medical University, 2011, 0(4): 280-286 |
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| Authors: | Journal of Biomedical Research |
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| Abstract: | ![]()
The present study investigated the antiarrhythmic activity of alcoholic extract of Tinospora cordifolia (T.cordifolia) in CaCl 2 induced arrhythmia.CaCl 2 (25 mg/kg) was administered by intravenous infusion (iv) to produce arrhythmia in rats.The animals were then treated with T.cordifolia extract (150,250,and 450 mg/kg) and verapamil (5 mg/kg,iv).Lead II electrocardiogram was monitored.Plasma calcium,sodium and potassium levels were measured.In CaCl 2 induced arrhythmia,heart rate was decreased by 41.10%,T.... |
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| Keywords: | Tinospora cordifolia arrhythmia cardioprotection. |
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