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| 氯氮平与氯丙嗪致粒细胞下降的临床调查 | |
| 引用本文： | 刘三源. 氯氮平与氯丙嗪致粒细胞下降的临床调查[J]. 中国民康医学, 1996, 0(2) |
| 作者姓名： | 刘三源 |
| 作者单位： | 南京医科大学脑科医院 |
| 摘 要： | 本文调查了１９８２年１月～１９９５年５月本院１１６４７例使用氯丙嗪与氯氮平的住院病人病案。药物所致的粒细胞下降２２例。治疗前ＷＢＣ＜６×１０９／Ｌ者易于发生。氯氮平致粒细胞下降的发生率和死亡率均高于氯丙嗪。预防与控制继发感染是治疗关键，停药后ＷＢＣ一般在１５天左右恢复正常。 |
| 关 键 词： | 氯丙嗪，氯氮平，粒细胞减少，粒细胞缺乏 |
Clinical Survey of Granulocyte DecreaseCaused by Clozapine and Chlorpromazine |
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| Liu San-yuan. Clinical Survey of Granulocyte DecreaseCaused by Clozapine and Chlorpromazine[J]. medical journal of chinese peoples health, 1996, 0(2) | |
| Authors: | Liu San-yuan |
| Affiliation: | Liu San-yuan |
| Abstract: | 1647 psychiatric inptients admitted at NanjingMedical College Brain Hospital in January 1982 toMay 1995 were investigated. The results showedthat 22 of them had decreased granul cyte, thosewhose WBC 6 10 /L were easy to suffer thisproblem, the incidence and death rate of granulo-cyte decrease caused by clozapine were higher thanthose by chlorpromazine. It suggests that prevent-ing and controlling secondary infection is the keytreatment , WBC can retun normal in 15 days afterstopping the medicine. |
| Keywords: | Chlopromazine clozapine granulocyte decrease agranulocyte |
| 本文献已被 CNKI 等数据库收录！ | |