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人脑运动皮层功能磁共振成像研究
引用本文:范骏,龚洪翰,王进华,曾献军. 人脑运动皮层功能磁共振成像研究[J]. 实用临床医学(江西), 2008, 9(2): 96-98
作者姓名:范骏  龚洪翰  王进华  曾献军
作者单位:南昌大学医学院门诊部CT室 南昌330006(范骏),南昌大学第一附属医院影像科 南昌330006(龚洪翰,王进华,曾献军)
摘    要:目的采用功能用磁共振成像(fMRI)回波平面(EPI)技术,研究人脑运动皮质血氧水平依赖(BOLD)的功能磁共振成像。方法27名正常健康志愿者,右手挤压橡皮圈,在运动和静止两种对比条件下,采集运动皮层的回波平面图像(BOLD-fMRI)。分析运动状态和非运动状态信号对比的脑功能图像。结果fMRI图像显示运动刺激下脑功能活动激活区主要位于对侧感觉运动皮质区、辅助运动区等。结论fMRI可用于研究活体人脑各功能区的活动,fMRI可对运动刺激下的人脑运动皮质进行初步定位。

关 键 词:磁共振脑功能活动成像  躯体感觉皮质  回波平面成像
文章编号:1009-8194(2008)02-0096-03
收稿时间:2007-09-30
修稿时间:2007-09-30

Investigation of the Human Brain Motor Cortex by Functional Magnetic Resonance Imaging
FAN Jun,GONG Hong-han,WANG Jin-hua,ZENG Xian-jun. Investigation of the Human Brain Motor Cortex by Functional Magnetic Resonance Imaging[J]. Practical Clinical Medicine, 2008, 9(2): 96-98
Authors:FAN Jun  GONG Hong-han  WANG Jin-hua  ZENG Xian-jun
Affiliation:FAN Jun, GONG Hong-han, WANG Jin-hua, ZENG Xian-jun(1. CT Room ,Outpatient Department of Medical College ; 2. Department of Imaging, the First Affiliated Hospital ,Nanchang University ,Nanchang 330006,China)
Abstract:Objective To explore functional magnetic resonance imaging(fMRI)of motor cortex by using echo planar imaging(EPI) and blood oxygenation level dependent(BOLD)contrast.Methods Twenty-seven healthy volunteers were included in this experiment.Motor stimulation was induced by repetitive pressing the rubber roll of right hand of the volunteers.The echo planar images of the motor cortex were acquired at motion stimulation and rest phases.T-test analysis was used to statistically generate the activation map.Results The activation areas were found in contralateral sensorimotor area,bilateral supplementary motor area and so on.Conclusion fMRI could be used to study human functional cortex.A preliminary location of the motor cortex can be acquired through motor stimulation.
Keywords:fMRI  motor cortex  EPI
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