The free cytoplasmic Ca2+ levels in Duchenne muscular dystrophy lymphocytes |
| |
| Authors: | Klip A Elder B Ruiz-Funes H P Buchwald M Grinstein S |
| |
| Institution: | Department of Neurology, Research Institute, Hospital for Sick Children, University of Toronto, Ontario, Canada. |
| |
| Abstract: | An increased cellular Ca2+ content has been associated with Duchenne muscular dystrophy (DMD). However, estimates of the free cytoplasmic Ca2+ concentration (Ca2+]i) in cells of DMD patients were not available. We compared the Ca2+]i levels of normal and DMD peripheral blood lymphocytes and Epstein-Barr virus-transformed lymphoblasts using the novel probe, quin 2, an internally trapped fluorescent indicator. The Ca2+]i levels of normal and DMD cells were not significantly different. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
