|
|||||
|
|
ADOPTION OF MELD SCORE INCREASES THE NUMBER OF LIVER TRANSPLANT |
|
| Authors: | Lucas Souto NACIF Wellington ANDRAUS Rodrigo Bronze MARTINO Vinicius Rocha SANTOS Rafael Soares PINHEIRO Luciana BP HADDAD Luiz Carneiro D'ALBUQUERQUE |
| Affiliation: | From the Disciplina de Transplante de Órgãos do Aparelho Digestivo – Laboratório de Investigações Médicas (LIM 37), Departamento de Gastroenterologia, Faculdade de Medicina, Universidade de São Paulo (Liver and Gastrointestinal Transplant Division, Department of Gastroenterology, School of Medicine, University of São Paulo), São Paulo, SP, Brazil |
| Abstract: | BackgroundLiver transplantation is performed at large transplant centers worldwide as atherapeutic intervention for patients with end-stage liver diseases.AimTo analyze the outcomes and incidence of liver transplantation performed at theUniversity of São Paulo and to compare those with the State of SãoPaulo before and after adoption of the Model for End-Stage Liver Disease (MELD)score.MethodEvaluation of the number of liver transplantations before and after adoption ofthe MELD score. Mean values and standard deviations were used to analyze normallydistributed variables. The incidence results were compared with those of the Stateof São Paulo.ResultsThere was a high prevalence of male patients, with a predominance of middle-aged.The main indication for liver transplantation was hepatitis C cirrhosis. The meanand median survival rates and overall survival over ten and five years weresimilar between the groups (p>0.05). The MELD score increased over the courseof the study period for patients who underwent liver transplantation (p>0.05).There were an increased number of liver transplants after adoption of the MELDscore at this institution and in the State of São Paulo (p<0.001).ConclusionThe adoption of the MELD score led to increase the number of liver transplantsperformed in São Paulo. |
| Keywords: | Transplantation Disease General surgery |