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Survivin蛋白在乳腺癌中的表达及意义
引用本文:宋宇豹,牛清华,郑彩虹. Survivin蛋白在乳腺癌中的表达及意义[J]. 山西职工医学院学报, 2008, 18(1): 11-12
作者姓名:宋宇豹  牛清华  郑彩虹
作者单位:山西医科大学,山西,太原,030001
摘    要:
目的:探讨Survivin蛋白在乳腺癌组织中表达的临床意义。方法:应用免疫组织化学法(SP法)检测60例乳腺癌组织和15例乳腺增生症中Survivin蛋白的表达。结果:Survivin在乳腺癌组织中表达的阳性率为68.3%(41/60),Survivin在乳腺癌中的阳性表达率明显高于乳腺增生症20.0%(3/15)(P〈0.05);但与患者乳腺癌组织组织学分型、淋巴结转移无明显相关性。结论:Survivin蛋白表达异常在乳腺癌发生中可能有一定的作用。

关 键 词:Survivin蛋白  乳腺癌  乳腺增生症  免疫组织化学法
文章编号:1671-0126(2008)01-0011-02

Expressions and the Significance of Survivin Protein in Breast Cancer
SONG Yubao,NIU Qinghua,ZHENG Caihong. Expressions and the Significance of Survivin Protein in Breast Cancer[J]. Journal of Shanxi Medical College For Continuing Education, 2008, 18(1): 11-12
Authors:SONG Yubao  NIU Qinghua  ZHENG Caihong
Affiliation:Shanxi Medical University;Taiyuan 030001;Shanxi;China
Abstract:
Objective: To investigate the expressions and the clinical significance of Survivin protein in breast cancer.Methods: The expressions of Survivin protein were detected in 60 cases with breast cancer and 15 cases with mammary gland hyperplasia by immunohistochemical method(SP method).Results: The positive rate of Survivin expressions was 68.3%(41/60)in breast cancer and was higher than that of mammary gland hyperplasia 20.0%(3/15)(P<0.05),but it had no obvious correlation with histological classification and...
Keywords:Survivin protein  breast cancer  mammary gland hyperplasia  immunohistochemical method  
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